An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene

An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene

Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to d...

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Bibliographic Details
Main Authors: Krešimir Molčanov, Slovenko Polanc, Maja Osmak, Biserka Kojić-Prodić
Format: Article
Language:English
Published: Slovenian Chemical Society 2015-04-01
Series:Acta Chimica Slovenica
Subjects:
axial chirality
enantiomeric disorder
molecular structure
crystal structure
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/1420
Description
Summary:Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA
ISSN:1318-0207
1580-3155

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