An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene
Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to d...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Slovenian Chemical Society
2015-04-01
|
| Series: | Acta Chimica Slovenica |
| Subjects: | |
| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/1420 |
| _version_ | 1818057720566120448 |
|---|---|
| author | Krešimir Molčanov Slovenko Polanc Maja Osmak Biserka Kojić-Prodić |
| author_facet | Krešimir Molčanov Slovenko Polanc Maja Osmak Biserka Kojić-Prodić |
| author_sort | Krešimir Molčanov |
| collection | DOAJ |
| description | Biologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA |
| first_indexed | 2024-12-10T12:49:13Z |
| format | Article |
| id | doaj.art-9cb7015b09f342c09dcacaff393f2897 |
| institution | Directory Open Access Journal |
| issn | 1318-0207 1580-3155 |
| language | English |
| last_indexed | 2024-12-10T12:49:13Z |
| publishDate | 2015-04-01 |
| publisher | Slovenian Chemical Society |
| record_format | Article |
| series | Acta Chimica Slovenica |
| spelling | doaj.art-9cb7015b09f342c09dcacaff393f28972022-12-22T01:48:19ZengSlovenian Chemical SocietyActa Chimica Slovenica1318-02071580-31552015-04-0162237137710.17344/acsi.2015.1420253An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazeneKrešimir Molčanov0Slovenko Polanc1Maja Osmak2Biserka Kojić-Prodić3Rudjer Bošković InstituteFaculty of Chemistry and Chemical Technology, University of LjubljanaRudjer Bošković InstituteRudjer Bošković InstituteBiologically active 4-nitro-substituted 1,3-diaryltriazene, a chemical analogue of 1,3-bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNAhttps://journals.matheo.si/index.php/ACSi/article/view/1420axial chiralityenantiomeric disordermolecular structurecrystal structure |
| spellingShingle | Krešimir Molčanov Slovenko Polanc Maja Osmak Biserka Kojić-Prodić An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene Acta Chimica Slovenica axial chirality enantiomeric disorder molecular structure crystal structure |
| title | An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene |
| title_full | An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene |
| title_fullStr | An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene |
| title_full_unstemmed | An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene |
| title_short | An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3-acetyl-1,3-bis(2-chloro-4-nitrophenyl)-1E-triazene |
| title_sort | axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3 acetyl 1 3 bis 2 chloro 4 nitrophenyl 1e triazene |
| topic | axial chirality enantiomeric disorder molecular structure crystal structure |
| url | https://journals.matheo.si/index.php/ACSi/article/view/1420 |
| work_keys_str_mv | AT kresimirmolcanov anaxialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT slovenkopolanc anaxialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT majaosmak anaxialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT biserkakojicprodic anaxialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT kresimirmolcanov axialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT slovenkopolanc axialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT majaosmak axialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene AT biserkakojicprodic axialchiralityanddisorderofpositionalisomersinacrystalofhighlycytotoxic3acetyl13bis2chloro4nitrophenyl1etriazene |