Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis
Background: Patients suffering from complete colonic aganglionosis (TCA) require the best surgical care possible. Only a few studies reported J-Pouch repair as the primary reconstructive surgery in TCA patients. This study adds to the current literature a thorough clinical and functional outcomes gr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-01-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/1/101 |
| _version_ | 1797495015831764992 |
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| author | Konrad Reinshagen Gunter Burmester Johanna Hagens Thomas Franz Krebs Christian Tomuschat |
| author_facet | Konrad Reinshagen Gunter Burmester Johanna Hagens Thomas Franz Krebs Christian Tomuschat |
| author_sort | Konrad Reinshagen |
| collection | DOAJ |
| description | Background: Patients suffering from complete colonic aganglionosis (TCA) require the best surgical care possible. Only a few studies reported J-Pouch repair as the primary reconstructive surgery in TCA patients. This study adds to the current literature a thorough clinical and functional outcomes group. Methods: Between 2011 and 2021, medical records of Hirschsprung disease (HD) patients who underwent J-Pouch reconstruction during infancy (n = 12) were reviewed. In close follow-up, bowel function and satisfaction with operation results were evaluated. The median age at the time of J-Pouch reconstruction was 16 months, and covering ileostomies were closed four months later. There were no postoperative problems. After the final repair, Pouch-related problems (PRP) occurred in 27% of the children and were treated conservatively. There was no histological evidence of pouchitis in any of the individuals. The median 24-h stooling frequency was 4–5 at the latest follow-up 51 months following enterostomy closure. Conclusions: The current study’s findings support the existing literature and advocate for J-pouch repair in TCA patients. However, more research will be needed to determine the best time to undergo pouch surgery and ileostomy closure in TCA patients. |
| first_indexed | 2024-03-10T01:42:28Z |
| format | Article |
| id | doaj.art-9cbae9b41bad4dca9771c2ffac04aa02 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-10T01:42:28Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-9cbae9b41bad4dca9771c2ffac04aa022023-11-23T13:21:55ZengMDPI AGChildren2227-90672022-01-019110110.3390/children9010101Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic AganglionosisKonrad Reinshagen0Gunter Burmester1Johanna Hagens2Thomas Franz Krebs3Christian Tomuschat4Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Pediatrics, Altonaer Kinderkrankenhaus, 22763 Hamburg, GermanyDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyDepartment of Pediatric Surgery, Children’s Hospital of Eastern Switzerland, 9006 St. Gallen, SwitzerlandDepartment of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, GermanyBackground: Patients suffering from complete colonic aganglionosis (TCA) require the best surgical care possible. Only a few studies reported J-Pouch repair as the primary reconstructive surgery in TCA patients. This study adds to the current literature a thorough clinical and functional outcomes group. Methods: Between 2011 and 2021, medical records of Hirschsprung disease (HD) patients who underwent J-Pouch reconstruction during infancy (n = 12) were reviewed. In close follow-up, bowel function and satisfaction with operation results were evaluated. The median age at the time of J-Pouch reconstruction was 16 months, and covering ileostomies were closed four months later. There were no postoperative problems. After the final repair, Pouch-related problems (PRP) occurred in 27% of the children and were treated conservatively. There was no histological evidence of pouchitis in any of the individuals. The median 24-h stooling frequency was 4–5 at the latest follow-up 51 months following enterostomy closure. Conclusions: The current study’s findings support the existing literature and advocate for J-pouch repair in TCA patients. However, more research will be needed to determine the best time to undergo pouch surgery and ileostomy closure in TCA patients.https://www.mdpi.com/2227-9067/9/1/101hirschsprung diseaseTotal Colonic AganglionosisJ-pouch reconstructionrestora-tive proctocolectomy |
| spellingShingle | Konrad Reinshagen Gunter Burmester Johanna Hagens Thomas Franz Krebs Christian Tomuschat Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis Children hirschsprung disease Total Colonic Aganglionosis J-pouch reconstruction restora-tive proctocolectomy |
| title | Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis |
| title_full | Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis |
| title_fullStr | Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis |
| title_full_unstemmed | Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis |
| title_short | Colectomy Followed by J-Pouch Reconstruction to Correct Total Colonic Aganglionosis |
| title_sort | colectomy followed by j pouch reconstruction to correct total colonic aganglionosis |
| topic | hirschsprung disease Total Colonic Aganglionosis J-pouch reconstruction restora-tive proctocolectomy |
| url | https://www.mdpi.com/2227-9067/9/1/101 |
| work_keys_str_mv | AT konradreinshagen colectomyfollowedbyjpouchreconstructiontocorrecttotalcolonicaganglionosis AT gunterburmester colectomyfollowedbyjpouchreconstructiontocorrecttotalcolonicaganglionosis AT johannahagens colectomyfollowedbyjpouchreconstructiontocorrecttotalcolonicaganglionosis AT thomasfranzkrebs colectomyfollowedbyjpouchreconstructiontocorrecttotalcolonicaganglionosis AT christiantomuschat colectomyfollowedbyjpouchreconstructiontocorrecttotalcolonicaganglionosis |