Theanine, a Tea-Leaf-Specific Amino Acid, Alleviates Stress through Modulation of Npas4 Expression in Group-Housed Older Mice

Theanine, a Tea-Leaf-Specific Amino Acid, Alleviates Stress through Modulation of Npas4 Expression in Group-Housed Older Mice

Group rearing is a common housing condition, but group-housed older mice show increased adrenal hypertrophy, a marker of stress. However, the ingestion of theanine, an amino acid unique to tea leaves, suppressed stress. We aimed to elucidate the mechanism of theanine’s stress-reducing effects using...

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Bibliographic Details
Main Authors: Keiko Unno, Kyoko Taguchi, Tomokazu Konishi, Makoto Ozeki, Yoriyuki Nakamura
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
DNA methyltransferase
glucocorticoid receptor
group housing
IL-1β
Npas4
REST
Online Access:https://www.mdpi.com/1422-0067/24/4/3983

Internet

https://www.mdpi.com/1422-0067/24/4/3983

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