Vaginal Microbiome Dynamics of Cows in Different Parities
At present, there is still room for research on the relationship between the vaginal microbiome and the reproductive health of dairy cows. In this study, high-throughput 16S rRNA sequencing technology was used to explore the differences of bacterial communities of dairy cows of different births, gai...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/18/2880 |
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| author | Jiale Ni Jie Wang Kaisen Zhao Yang Chen Siqi Xia Songjia Lai |
| author_facet | Jiale Ni Jie Wang Kaisen Zhao Yang Chen Siqi Xia Songjia Lai |
| author_sort | Jiale Ni |
| collection | DOAJ |
| description | At present, there is still room for research on the relationship between the vaginal microbiome and the reproductive health of dairy cows. In this study, high-throughput 16S rRNA sequencing technology was used to explore the differences of bacterial communities of dairy cows of different births, gain a deeper understanding of cow reproductive physiology, and maintain cow health. With the increase in parity, the number of vaginal flora decreased from 3511 to 469, but the number of species increased significantly, and Chao1 increased from 1226.41 ± 345.40 to 1467.76 ± 269.76. There was a significant difference in the number of vaginal microbiome functions between uncounted cows and calving cows. There was no significant difference in microbial diversity in calves. The relative abundance variation of vaginal microbiota in high-parity cows is less than that in low-parity cows. The amino acid metabolism of calves increased, the endocrine function of high-parity cows was enhanced, and the function of the vaginal microbiome increased after the first delivery, which gradually decreased with the increase in parity. This study also found that <i>Methanobacteria</i> and <i>Caviibacter</i> may be involved in amino acid metabolism and endocrine function, and they may play a key role in cow reproduction. This study provides an important theoretical basis for studying changes in vaginal microorganisms in dairy cows, improves the understanding of reproductive health and production performance, and provides a scientific basis for improving the reproductive management of dairy cows. |
| first_indexed | 2024-03-10T23:07:42Z |
| format | Article |
| id | doaj.art-9cbea89ddbc2457487ad5306546809ee |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-10T23:07:42Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-9cbea89ddbc2457487ad5306546809ee2023-11-19T09:14:52ZengMDPI AGAnimals2076-26152023-09-011318288010.3390/ani13182880Vaginal Microbiome Dynamics of Cows in Different ParitiesJiale Ni0Jie Wang1Kaisen Zhao2Yang Chen3Siqi Xia4Songjia Lai5College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaCollege of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, ChinaAt present, there is still room for research on the relationship between the vaginal microbiome and the reproductive health of dairy cows. In this study, high-throughput 16S rRNA sequencing technology was used to explore the differences of bacterial communities of dairy cows of different births, gain a deeper understanding of cow reproductive physiology, and maintain cow health. With the increase in parity, the number of vaginal flora decreased from 3511 to 469, but the number of species increased significantly, and Chao1 increased from 1226.41 ± 345.40 to 1467.76 ± 269.76. There was a significant difference in the number of vaginal microbiome functions between uncounted cows and calving cows. There was no significant difference in microbial diversity in calves. The relative abundance variation of vaginal microbiota in high-parity cows is less than that in low-parity cows. The amino acid metabolism of calves increased, the endocrine function of high-parity cows was enhanced, and the function of the vaginal microbiome increased after the first delivery, which gradually decreased with the increase in parity. This study also found that <i>Methanobacteria</i> and <i>Caviibacter</i> may be involved in amino acid metabolism and endocrine function, and they may play a key role in cow reproduction. This study provides an important theoretical basis for studying changes in vaginal microorganisms in dairy cows, improves the understanding of reproductive health and production performance, and provides a scientific basis for improving the reproductive management of dairy cows.https://www.mdpi.com/2076-2615/13/18/2880high-throughput 16S rRNA sequencingcowvaginal microorganismsdifferent parities |
| spellingShingle | Jiale Ni Jie Wang Kaisen Zhao Yang Chen Siqi Xia Songjia Lai Vaginal Microbiome Dynamics of Cows in Different Parities Animals high-throughput 16S rRNA sequencing cow vaginal microorganisms different parities |
| title | Vaginal Microbiome Dynamics of Cows in Different Parities |
| title_full | Vaginal Microbiome Dynamics of Cows in Different Parities |
| title_fullStr | Vaginal Microbiome Dynamics of Cows in Different Parities |
| title_full_unstemmed | Vaginal Microbiome Dynamics of Cows in Different Parities |
| title_short | Vaginal Microbiome Dynamics of Cows in Different Parities |
| title_sort | vaginal microbiome dynamics of cows in different parities |
| topic | high-throughput 16S rRNA sequencing cow vaginal microorganisms different parities |
| url | https://www.mdpi.com/2076-2615/13/18/2880 |
| work_keys_str_mv | AT jialeni vaginalmicrobiomedynamicsofcowsindifferentparities AT jiewang vaginalmicrobiomedynamicsofcowsindifferentparities AT kaisenzhao vaginalmicrobiomedynamicsofcowsindifferentparities AT yangchen vaginalmicrobiomedynamicsofcowsindifferentparities AT siqixia vaginalmicrobiomedynamicsofcowsindifferentparities AT songjialai vaginalmicrobiomedynamicsofcowsindifferentparities |