Ac-EAZY! Towards GMP-Compliant Module Syntheses of <sup>225</sup>Ac-Labeled Peptides for Clinical Application

Ac-EAZY! Towards GMP-Compliant Module Syntheses of <sup>225</sup>Ac-Labeled Peptides for Clinical Application

The application of <sup>225</sup>Ac (half-life T<sub>1/2</sub> = 9.92 d) dramatically reduces the activity used for peptide receptor radionuclide therapy by a factor of 1000 in comparison to <sup>90</sup>Y, <sup>177</sup>Lu or <sup>188</sup>...

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Bibliographic Details
Main Authors: Marc Pretze, Falk Kunkel, Roswitha Runge, Robert Freudenberg, Anja Braune, Holger Hartmann, Uwe Schwarz, Claudia Brogsitter, Jörg Kotzerke
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceuticals
Subjects:
actinium-225
TATE
PSMA
module synthesis
endoradiotherapy
GMP
Online Access:https://www.mdpi.com/1424-8247/14/7/652

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