PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling

Arginine methylation is a post-translational modification that regulates many biological processes. However, the role of arginine methylation in immune cells is not well studied. Here we report an essential role of protein arginine methyltransferase 5 (PRMT5) in T cell homeostasis and activation-ind...

Full description

Bibliographic Details
Main Authors: Yukinori Tanaka, Yasuhiro Nagai, Mariko Okumura, Mark I. Greene, Taku Kambayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
arginine methylation
PRMT5
T cell survival
T cell proliferation
T cell development
cytokine signaling
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00621/full

Similar Items

Similar Items