ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program
According to DSM 5, generalized anxiety disorder (GAD) is characterized by excessive, uncontrollable worry about various topics that occupies the majority of the subject’s time for a period of at least six months. The aforementioned state causes distress and/or functional impairments. This paper pre...
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MDPI AG
2022-09-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/9/1174 |
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| author | Nikolaos C. Zygouris Filippos Vlachos Georgios I. Stamoulis |
| author_facet | Nikolaos C. Zygouris Filippos Vlachos Georgios I. Stamoulis |
| author_sort | Nikolaos C. Zygouris |
| collection | DOAJ |
| description | According to DSM 5, generalized anxiety disorder (GAD) is characterized by excessive, uncontrollable worry about various topics that occupies the majority of the subject’s time for a period of at least six months. The aforementioned state causes distress and/or functional impairments. This paper presents the outcomes of a pilot study that evaluated the implementation of cognitive behavioral therapy (CBT) and CBT with an SSRIs intervention program. The participants comprised 16 children and adolescents with GAD (8 males and 8 females) matched with 16 typically developing peers (8 males and 8 females) aged from 10 to 16 years old (M = 12.56 SD = 2.18). Baseline assessment consisted of event related potentials (ERPs), which indicated that participants with GAD presented cognitive deficits in attention and memory, as they exhibited longer P300 latencies. Following treatment with the CBT program and/or medication, children and adolescents with GAD did not present statistically significantly longer P300 latencies and reaction times in comparison to the control group. Lastly, children and adolescents who followed the CBT program or the CBT program with psychopharmacological assistance did not reveal statistically significant differences in 13 out of 15 topographic brain areas and in reaction time. |
| first_indexed | 2024-03-10T00:33:36Z |
| format | Article |
| id | doaj.art-9cc4f8f4e560437d8755fb8e5d21d6e2 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T00:33:36Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-9cc4f8f4e560437d8755fb8e5d21d6e22023-11-23T15:20:27ZengMDPI AGBrain Sciences2076-34252022-09-01129117410.3390/brainsci12091174ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention ProgramNikolaos C. Zygouris0Filippos Vlachos1Georgios I. Stamoulis2Department of Computer Science and Telecommunications, University of Thessaly, 35131 Lamia, GreeceSpecial Education Department, University of Thessaly, 35221 Volos, GreeceDepartment of Electrical and Computer Engineering, University of Thessaly, 38334 Volos, GreeceAccording to DSM 5, generalized anxiety disorder (GAD) is characterized by excessive, uncontrollable worry about various topics that occupies the majority of the subject’s time for a period of at least six months. The aforementioned state causes distress and/or functional impairments. This paper presents the outcomes of a pilot study that evaluated the implementation of cognitive behavioral therapy (CBT) and CBT with an SSRIs intervention program. The participants comprised 16 children and adolescents with GAD (8 males and 8 females) matched with 16 typically developing peers (8 males and 8 females) aged from 10 to 16 years old (M = 12.56 SD = 2.18). Baseline assessment consisted of event related potentials (ERPs), which indicated that participants with GAD presented cognitive deficits in attention and memory, as they exhibited longer P300 latencies. Following treatment with the CBT program and/or medication, children and adolescents with GAD did not present statistically significantly longer P300 latencies and reaction times in comparison to the control group. Lastly, children and adolescents who followed the CBT program or the CBT program with psychopharmacological assistance did not reveal statistically significant differences in 13 out of 15 topographic brain areas and in reaction time.https://www.mdpi.com/2076-3425/12/9/1174children and adolescents with anxietyevent related potentialsCBT program |
| spellingShingle | Nikolaos C. Zygouris Filippos Vlachos Georgios I. Stamoulis ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program Brain Sciences children and adolescents with anxiety event related potentials CBT program |
| title | ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program |
| title_full | ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program |
| title_fullStr | ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program |
| title_full_unstemmed | ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program |
| title_short | ERPs in Children and Adolescents with Generalized Anxiety Disorder: Before and after an Intervention Program |
| title_sort | erps in children and adolescents with generalized anxiety disorder before and after an intervention program |
| topic | children and adolescents with anxiety event related potentials CBT program |
| url | https://www.mdpi.com/2076-3425/12/9/1174 |
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