Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia
Serious complications in both mother and newborn arising as a result of fetal macrosomia indicate the need for early diagnosis and prevention. Unfortunately, current predictors, such as fetal biometry, fundal height, and amniotic fluid index, appear to be insufficient. Therefore, we decided to asses...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/5/949 |
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| author | Bartosz Szmyd Małgorzata Biedrzycka Filip Franciszek Karuga Magdalena Rogut Iwona Strzelecka Maria Respondek-Liberska |
| author_facet | Bartosz Szmyd Małgorzata Biedrzycka Filip Franciszek Karuga Magdalena Rogut Iwona Strzelecka Maria Respondek-Liberska |
| author_sort | Bartosz Szmyd |
| collection | DOAJ |
| description | Serious complications in both mother and newborn arising as a result of fetal macrosomia indicate the need for early diagnosis and prevention. Unfortunately, current predictors, such as fetal biometry, fundal height, and amniotic fluid index, appear to be insufficient. Therefore, we decided to assess the predictive potential of interventricular septal thickness (IVST), as measured at ≥33 weeks of gestation. Two hundred and ninety-nine patients met the inclusion criteria: complete medical history including all necessary measurements—namely, IVST obtained by M-mode echocardiography, fetal biometry, and birth weight. The Statistica 13.1 PL software was used to generate the receiver operating curve. The optimal cut-off point (IVST of 4.7 mm) was selected using the Youden index method. The analysis of fetal biometry abnormalities resulted in 46.6% of macrosomia cases being correctly predicted; however, IVST analysis detected 71.4% of cases. IVST at ≥4.7 mm appears to have a higher sensitivity and negative predictive value (NPV) than routine ultrasound. |
| first_indexed | 2024-03-09T06:06:30Z |
| format | Article |
| id | doaj.art-9cc584b8956e49d69d0df146cb503662 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T06:06:30Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-9cc584b8956e49d69d0df146cb5036622023-12-03T12:03:42ZengMDPI AGJournal of Clinical Medicine2077-03832021-03-0110594910.3390/jcm10050949Interventricular Septal Thickness as a Diagnostic Marker of Fetal MacrosomiaBartosz Szmyd0Małgorzata Biedrzycka1Filip Franciszek Karuga2Magdalena Rogut3Iwona Strzelecka4Maria Respondek-Liberska5Department of Pediatrics, Oncology, and Hematology, Medical University of Lodz, 91-738 Łódź, PolandStudent’s Scientific Association Prenatal Cardiology, Medical University of Lodz, 93-338 Łódź, PolandStudent’s Scientific Association Prenatal Cardiology, Medical University of Lodz, 93-338 Łódź, PolandStudent’s Scientific Association Prenatal Cardiology, Medical University of Lodz, 93-338 Łódź, PolandDepartment of Diagnosis and Prevention Fetal Malformations, Medical University of Lodz, 93-338 Łódź, PolandDepartment of Diagnosis and Prevention Fetal Malformations, Medical University of Lodz, 93-338 Łódź, PolandSerious complications in both mother and newborn arising as a result of fetal macrosomia indicate the need for early diagnosis and prevention. Unfortunately, current predictors, such as fetal biometry, fundal height, and amniotic fluid index, appear to be insufficient. Therefore, we decided to assess the predictive potential of interventricular septal thickness (IVST), as measured at ≥33 weeks of gestation. Two hundred and ninety-nine patients met the inclusion criteria: complete medical history including all necessary measurements—namely, IVST obtained by M-mode echocardiography, fetal biometry, and birth weight. The Statistica 13.1 PL software was used to generate the receiver operating curve. The optimal cut-off point (IVST of 4.7 mm) was selected using the Youden index method. The analysis of fetal biometry abnormalities resulted in 46.6% of macrosomia cases being correctly predicted; however, IVST analysis detected 71.4% of cases. IVST at ≥4.7 mm appears to have a higher sensitivity and negative predictive value (NPV) than routine ultrasound.https://www.mdpi.com/2077-0383/10/5/949fetal macrosomiainterventricular septal thicknessprenatal cardiology |
| spellingShingle | Bartosz Szmyd Małgorzata Biedrzycka Filip Franciszek Karuga Magdalena Rogut Iwona Strzelecka Maria Respondek-Liberska Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia Journal of Clinical Medicine fetal macrosomia interventricular septal thickness prenatal cardiology |
| title | Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia |
| title_full | Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia |
| title_fullStr | Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia |
| title_full_unstemmed | Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia |
| title_short | Interventricular Septal Thickness as a Diagnostic Marker of Fetal Macrosomia |
| title_sort | interventricular septal thickness as a diagnostic marker of fetal macrosomia |
| topic | fetal macrosomia interventricular septal thickness prenatal cardiology |
| url | https://www.mdpi.com/2077-0383/10/5/949 |
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