Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation

Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation

Total parenteral nutrition (TPN), a commonly used treatment for patients who cannot receive enteral nutrition, is associated with significant septic complications due in part to a loss of epithelial barrier function (EBF). While the underlying mechanisms of TPN-related epithelial changes are poorly...

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Bibliographic Details
Main Authors: Farokh R. Demehri, Meredith eBarrett, Matthew W. Ralls, Eiichi A. Miyasaka, Yongjia eFeng, Daniel H. Teitelbaum
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Apoptosis
Parenteral Nutrition
microbiome
small intestine
epithelial barrier function
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00105/full

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