The Mechanism of miRNAs in Liver Fibrosis
MicroRNAs(miRNAs) are involved in the pathophysiological processes of many diseases. Stably present in cells, tissues and blood, they can be used as potential markers of many diseases. They play an important role in the pathogenesis of liver fibrosis caused by various chronic liver diseases. It has...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Medical Journal of Peking Union Medical College Hospital
2023-11-01
|
| Series: | Xiehe Yixue Zazhi |
| Subjects: | |
| Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0125 |
| _version_ | 1797405517750992896 |
|---|---|
| author | HUANG Lu WU Youbin NI Yiran LIU Mengyuan WU Jiangfeng ZHANG Yanqiong |
| author_facet | HUANG Lu WU Youbin NI Yiran LIU Mengyuan WU Jiangfeng ZHANG Yanqiong |
| author_sort | HUANG Lu |
| collection | DOAJ |
| description | MicroRNAs(miRNAs) are involved in the pathophysiological processes of many diseases. Stably present in cells, tissues and blood, they can be used as potential markers of many diseases. They play an important role in the pathogenesis of liver fibrosis caused by various chronic liver diseases. It has been shown that miRNAs can participate in the process of liver fibrosis by targeting the down-regulation of liver fibrosis-related gene expression. In this review, we discuss the research progress on the role of miRNAs in liver fibrosis, with the hope of providing reference for diagnosis and molecularly targeted treatment. |
| first_indexed | 2024-03-09T03:12:05Z |
| format | Article |
| id | doaj.art-9cc8747ca4404d4cba74f68d053c5291 |
| institution | Directory Open Access Journal |
| issn | 1674-9081 |
| language | zho |
| last_indexed | 2024-03-09T03:12:05Z |
| publishDate | 2023-11-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj.art-9cc8747ca4404d4cba74f68d053c52912023-12-04T02:47:34ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812023-11-011461251125710.12290/xhyxzz.2023-0125The Mechanism of miRNAs in Liver FibrosisHUANG LuWU Youbin0NI YiranLIU MengyuanWU JiangfengZHANG YanqiongYichang Renfu Pharmaceutical Co., Ltd., Yichang, Hubei 443000, ChinaMicroRNAs(miRNAs) are involved in the pathophysiological processes of many diseases. Stably present in cells, tissues and blood, they can be used as potential markers of many diseases. They play an important role in the pathogenesis of liver fibrosis caused by various chronic liver diseases. It has been shown that miRNAs can participate in the process of liver fibrosis by targeting the down-regulation of liver fibrosis-related gene expression. In this review, we discuss the research progress on the role of miRNAs in liver fibrosis, with the hope of providing reference for diagnosis and molecularly targeted treatment.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0125liver fibrosismicrornastherapeutic strategiestargeted delivery |
| spellingShingle | HUANG Lu WU Youbin NI Yiran LIU Mengyuan WU Jiangfeng ZHANG Yanqiong The Mechanism of miRNAs in Liver Fibrosis Xiehe Yixue Zazhi liver fibrosis micrornas therapeutic strategies targeted delivery |
| title | The Mechanism of miRNAs in Liver Fibrosis |
| title_full | The Mechanism of miRNAs in Liver Fibrosis |
| title_fullStr | The Mechanism of miRNAs in Liver Fibrosis |
| title_full_unstemmed | The Mechanism of miRNAs in Liver Fibrosis |
| title_short | The Mechanism of miRNAs in Liver Fibrosis |
| title_sort | mechanism of mirnas in liver fibrosis |
| topic | liver fibrosis micrornas therapeutic strategies targeted delivery |
| url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2023-0125 |
| work_keys_str_mv | AT huanglu themechanismofmirnasinliverfibrosis AT wuyoubin themechanismofmirnasinliverfibrosis AT niyiran themechanismofmirnasinliverfibrosis AT liumengyuan themechanismofmirnasinliverfibrosis AT wujiangfeng themechanismofmirnasinliverfibrosis AT zhangyanqiong themechanismofmirnasinliverfibrosis AT huanglu mechanismofmirnasinliverfibrosis AT wuyoubin mechanismofmirnasinliverfibrosis AT niyiran mechanismofmirnasinliverfibrosis AT liumengyuan mechanismofmirnasinliverfibrosis AT wujiangfeng mechanismofmirnasinliverfibrosis AT zhangyanqiong mechanismofmirnasinliverfibrosis |