A Peroxiredoxin Promotes H2O2 Signaling and Oxidative Stress Resistance by Oxidizing a Thioredoxin Family Protein
H2O2 can cause oxidative damage associated with age-related diseases such as diabetes and cancer but is also used to initiate diverse responses, including increased antioxidant gene expression. Despite significant interest, H2O2-signaling mechanisms remain poorly understood. Here, we present a mecha...
Main Authors: | Jonathon D. Brown, Alison M. Day, Sarah R. Taylor, Lewis E. Tomalin, Brian A. Morgan, Elizabeth A. Veal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713006207 |
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