Electrochemical synthesis of biaryls by reductive extrusion from N,N’-diarylureas

Abstract The synthesis of biaryl compounds by the transition-metal free coupling of arenes is an important contemporary challenge, aiming to avoid the toxicity and cost profiles associated with the metal catalysts commonly used in the synthesis of these pharmaceutically relevant motifs. In this pape...

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Bibliographic Details
Main Authors: Ellie Stammers, Chris D. Parsons, Jonathan Clayden, Alastair J. J. Lennox
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-40237-6