Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy
Infective endocarditis is a potentially life threatening condition. It is associated with high mortality and morbidity resulting mostly due to cardiorespiratory failure. Extracorporeal membrane oxygenation is a modality of treatment used to support hypoxic respiratory failure especially in patients...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2014-10-01
|
| Series: | Clinics and Practice |
| Subjects: | |
| Online Access: | https://www.clinicsandpractice.org/index.php/cp/article/view/670 |
| _version_ | 1818001786347192320 |
|---|---|
| author | Santhosh G. John Preethi William Sangeetha Murugapandian Bijin Thajudeen |
| author_facet | Santhosh G. John Preethi William Sangeetha Murugapandian Bijin Thajudeen |
| author_sort | Santhosh G. John |
| collection | DOAJ |
| description | Infective endocarditis is a potentially life threatening condition. It is associated with high mortality and morbidity resulting mostly due to cardiorespiratory failure. Extracorporeal membrane oxygenation is a modality of treatment used to support hypoxic respiratory failure especially in patients who are already on mechanical ventilation. Continuous renal replacement therapy is added mainly for maintaining fluid and electrolyte balance. Here we report a case series of patients diagnosed with infective endocarditis who were treated with combined extracorporeal membrane oxygenation and continuous renal replacement therapy. Three patients in the age group 20-60 years were admitted with clinical features suggestive of infective endocarditis. During the course of hospital stay they developed cardiorespiratory failure requiring mechanical ventilation and extracorporeal membrane oxygenation support for refractory hypoxia. It was complicated by heart failure, renal failure and fluid overload which required initiation of continuous renal replacement therapy. All the three patients succumbed in spite of the aggressive treatment. In addition to the role played by each complication, delayed start of continuous renal replacement therapy might have also contributed to the high mortality. Early initiation of continuous renal replacement therapy for management of fluid overload needs to be considered in the management of these critically ill patients. |
| first_indexed | 2024-04-14T03:37:50Z |
| format | Article |
| id | doaj.art-9ccfb76952b148e3ad8c4de00e152978 |
| institution | Directory Open Access Journal |
| issn | 2039-7275 2039-7283 |
| language | English |
| last_indexed | 2024-04-14T03:37:50Z |
| publishDate | 2014-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Clinics and Practice |
| spelling | doaj.art-9ccfb76952b148e3ad8c4de00e1529782022-12-22T02:14:40ZengMDPI AGClinics and Practice2039-72752039-72832014-10-014310.4081/cp.2014.670278Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapySanthosh G. John0Preethi William1Sangeetha Murugapandian2Bijin Thajudeen3Department of Medicine, University of Arizona Medical Center, Tucson, AZDepartment of Medicine, University of Arizona Medical Center, Tucson, AZDepartment of Medicine, University of Arizona Medical Center, Tucson, AZDepartment of Medicine, University of Arizona Medical Center, Tucson, AZInfective endocarditis is a potentially life threatening condition. It is associated with high mortality and morbidity resulting mostly due to cardiorespiratory failure. Extracorporeal membrane oxygenation is a modality of treatment used to support hypoxic respiratory failure especially in patients who are already on mechanical ventilation. Continuous renal replacement therapy is added mainly for maintaining fluid and electrolyte balance. Here we report a case series of patients diagnosed with infective endocarditis who were treated with combined extracorporeal membrane oxygenation and continuous renal replacement therapy. Three patients in the age group 20-60 years were admitted with clinical features suggestive of infective endocarditis. During the course of hospital stay they developed cardiorespiratory failure requiring mechanical ventilation and extracorporeal membrane oxygenation support for refractory hypoxia. It was complicated by heart failure, renal failure and fluid overload which required initiation of continuous renal replacement therapy. All the three patients succumbed in spite of the aggressive treatment. In addition to the role played by each complication, delayed start of continuous renal replacement therapy might have also contributed to the high mortality. Early initiation of continuous renal replacement therapy for management of fluid overload needs to be considered in the management of these critically ill patients.https://www.clinicsandpractice.org/index.php/cp/article/view/670acute renal failurefluid overloadcontinuous renal replacement therapyextracorporeal membrane oxygenationinfective endocarditis. |
| spellingShingle | Santhosh G. John Preethi William Sangeetha Murugapandian Bijin Thajudeen Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy Clinics and Practice acute renal failure fluid overload continuous renal replacement therapy extracorporeal membrane oxygenation infective endocarditis. |
| title | Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| title_full | Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| title_fullStr | Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| title_full_unstemmed | Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| title_short | Outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| title_sort | outcome of patients with infective endocarditis who were treated with extracorporeal membrane oxygenation and continuous renal replacement therapy |
| topic | acute renal failure fluid overload continuous renal replacement therapy extracorporeal membrane oxygenation infective endocarditis. |
| url | https://www.clinicsandpractice.org/index.php/cp/article/view/670 |
| work_keys_str_mv | AT santhoshgjohn outcomeofpatientswithinfectiveendocarditiswhoweretreatedwithextracorporealmembraneoxygenationandcontinuousrenalreplacementtherapy AT preethiwilliam outcomeofpatientswithinfectiveendocarditiswhoweretreatedwithextracorporealmembraneoxygenationandcontinuousrenalreplacementtherapy AT sangeethamurugapandian outcomeofpatientswithinfectiveendocarditiswhoweretreatedwithextracorporealmembraneoxygenationandcontinuousrenalreplacementtherapy AT bijinthajudeen outcomeofpatientswithinfectiveendocarditiswhoweretreatedwithextracorporealmembraneoxygenationandcontinuousrenalreplacementtherapy |