Nerve and Vascular Biomarkers in Skin Biopsies Differentiate Painful From Painless Peripheral Neuropathy in Type 2 Diabetes

Nerve and Vascular Biomarkers in Skin Biopsies Differentiate Painful From Painless Peripheral Neuropathy in Type 2 Diabetes

Painful diabetic peripheral neuropathy can be intractable with a major impact, yet the underlying pain mechanisms remain uncertain. A range of neuronal and vascular biomarkers was investigated in painful diabetic peripheral neuropathy (painful-DPN) and painless-DPN and used to differentiate painful-...

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Bibliographic Details
Main Authors: Pallai Shillo, Yiangos Yiangou, Philippe Donatien, Marni Greig, Dinesh Selvarajah, Iain D. Wilkinson, Praveen Anand, Solomon Tesfaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Pain Research
Subjects:
pain
biomarkers
skin
vascular
painful diabetic neuropathy
von Willebrand Factor
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2021.731658/full

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