Gas-blasting nanocapsules to accelerate carboplatin lysosome release and nucleus delivery for prostate cancer treatment

Gas-blasting nanocapsules to accelerate carboplatin lysosome release and nucleus delivery for prostate cancer treatment

To improve therapeutic effect and reduce severely side effects of carboplatin (CBP), the gas-generating nanocapsules were developed to accelerate CBP lysosome release and nucleus delivery. CBP/SB-NC was prepared by co-loading CBP and NaHCO3 (SB) in nanocapsules using w/o/w emulsification solvent eva...

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Bibliographic Details
Main Authors: Shunli Fu, Shuang Liang, Dandan Jiang, Rui Yang, Zipeng Zhang, Lili Chang, Xinke Zhang, Yongjun Liu, Na Zhang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Carboplatin
Nanocapsule
pH-responsive release
Gas-blasting
Prostate cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S181808762030372X

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