SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial–mesenchymal transition and mitochondrial function maintenance

SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial–mesenchymal transition and mitochondrial function maintenance

Abstract Background SQSTM1/p62 is a selective autophagy receptor that regulates multiple signaling pathways participating in the initiation and progression of tumors. Metastasis is still the main cause for intrahepatic cholangiocarcinoma (ICC)‐associated mortality. Hence, this study aimed to explore...

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Bibliographic Details
Main Authors: Jiafeng Chen, Zheng Gao, Xiaogang Li, Yinghong Shi, Zheng Tang, Weiren Liu, Xin Zhang, Ao Huang, Xuanming Luo, Qiang Gao, Guangyu Ding, Kang Song, Jian Zhou, Jia Fan, Xiutao Fu, Zhenbin Ding
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Cancer Medicine
Subjects:
EMT
intrahepatic cholangiocarcinoma
metastasis
mitophagy
SQSTM1/p62
Online Access:https://doi.org/10.1002/cam4.4908

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