Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease
Davood Soleimani,1 Golnaz Ranjbar,1,2 Reza Rezvani,1,3 Ladan Goshayeshi,4 Farkhonde Razmpour,1 Mohsen Nematy1 1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Biological and Environmental Sciences, Faculty of Life and Medical Scienc...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2019-03-01
|
| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Subjects: | |
| Online Access: | https://www.dovepress.com/dietary-patterns-in-relation-to-hepatic-fibrosis-among-patients-with-n-peer-reviewed-article-DMSO |
| _version_ | 1797934549822341120 |
|---|---|
| author | Soleimani D Ranjbar G Rezvani R Goshayeshi L Razmpour F Nematy M |
| author_facet | Soleimani D Ranjbar G Rezvani R Goshayeshi L Razmpour F Nematy M |
| author_sort | Soleimani D |
| collection | DOAJ |
| description | Davood Soleimani,1 Golnaz Ranjbar,1,2 Reza Rezvani,1,3 Ladan Goshayeshi,4 Farkhonde Razmpour,1 Mohsen Nematy1 1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Biological and Environmental Sciences, Faculty of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK; 3School of Nutrition, Faculté des Sciences de l’agriculture et de l’alimentation, Université Laval, Quebec, QC, Canada; 4Department of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Background: Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disorder that can progress to fibrosis. Several dietary patterns have been associated with histological features of NAFLD. However, little is known about the association between dietary patterns and hepatic fibrosis. Purpose: The current study aimed at identifying the relationship between major dietary patterns and hepatic fibrosis among patients with NAFLD. Subjects and methods: This cross-sectional study included 170 eligible subjects with NAFLD. Diet was evaluated using three 3-day dietary records during a 1-month period. Hepatic fibrosis was diagnosed using Fibroscan. Western, Iranian, and healthy dietary patterns were extracted using factor analysis. Results: After adjustment for other risk factors, adherence to a Western dietary pattern was associated with the higher odds of fibrosis (OR: 4.21; 95% CI: 1.63–8.31), whereas adherence to a healthy dietary pattern was associated with the lower odds of fibrosis (OR: 0.26; 95% CI: 0.10–0.49). Among main food groups, high intake of red meat, hydrogenated fats, and soft drinks was associated with the higher risk of fibrosis, whereas tea and coffee consumption had a protective role in hepatic fibrosis independent of other risk factors. Conclusion: The adherence to a healthy dietary pattern characterized by high intake of low-fat dairies, white meat, nuts, vegetables, fruits, and vegetable oils combined with coffee and tea consumption might be helpful in the nutritional strategies against hepatic fibrosis. Keywords: liver diseases, NAFLD, fibrosis, factor analysis, diet, dietary pattern |
| first_indexed | 2024-04-10T18:01:51Z |
| format | Article |
| id | doaj.art-9cdea62bea6747b483a0677843ebf200 |
| institution | Directory Open Access Journal |
| issn | 1178-7007 |
| language | English |
| last_indexed | 2024-04-10T18:01:51Z |
| publishDate | 2019-03-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj.art-9cdea62bea6747b483a0677843ebf2002023-02-02T15:30:52ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072019-03-01Volume 1231532444561Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver diseaseSoleimani DRanjbar GRezvani RGoshayeshi LRazmpour FNematy MDavood Soleimani,1 Golnaz Ranjbar,1,2 Reza Rezvani,1,3 Ladan Goshayeshi,4 Farkhonde Razmpour,1 Mohsen Nematy1 1Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran; 2Department of Biological and Environmental Sciences, Faculty of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK; 3School of Nutrition, Faculté des Sciences de l’agriculture et de l’alimentation, Université Laval, Quebec, QC, Canada; 4Department of Gastroenterology and Hepatology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Background: Nonalcoholic fatty liver disease (NAFLD) is a multifactorial disorder that can progress to fibrosis. Several dietary patterns have been associated with histological features of NAFLD. However, little is known about the association between dietary patterns and hepatic fibrosis. Purpose: The current study aimed at identifying the relationship between major dietary patterns and hepatic fibrosis among patients with NAFLD. Subjects and methods: This cross-sectional study included 170 eligible subjects with NAFLD. Diet was evaluated using three 3-day dietary records during a 1-month period. Hepatic fibrosis was diagnosed using Fibroscan. Western, Iranian, and healthy dietary patterns were extracted using factor analysis. Results: After adjustment for other risk factors, adherence to a Western dietary pattern was associated with the higher odds of fibrosis (OR: 4.21; 95% CI: 1.63–8.31), whereas adherence to a healthy dietary pattern was associated with the lower odds of fibrosis (OR: 0.26; 95% CI: 0.10–0.49). Among main food groups, high intake of red meat, hydrogenated fats, and soft drinks was associated with the higher risk of fibrosis, whereas tea and coffee consumption had a protective role in hepatic fibrosis independent of other risk factors. Conclusion: The adherence to a healthy dietary pattern characterized by high intake of low-fat dairies, white meat, nuts, vegetables, fruits, and vegetable oils combined with coffee and tea consumption might be helpful in the nutritional strategies against hepatic fibrosis. Keywords: liver diseases, NAFLD, fibrosis, factor analysis, diet, dietary patternhttps://www.dovepress.com/dietary-patterns-in-relation-to-hepatic-fibrosis-among-patients-with-n-peer-reviewed-article-DMSOWestern dietary patternHealthy dietary patternFactor analysisLiver Diseases |
| spellingShingle | Soleimani D Ranjbar G Rezvani R Goshayeshi L Razmpour F Nematy M Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease Diabetes, Metabolic Syndrome and Obesity Western dietary pattern Healthy dietary pattern Factor analysis Liver Diseases |
| title | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| title_full | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| title_fullStr | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| title_full_unstemmed | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| title_short | Dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| title_sort | dietary patterns in relation to hepatic fibrosis among patients with nonalcoholic fatty liver disease |
| topic | Western dietary pattern Healthy dietary pattern Factor analysis Liver Diseases |
| url | https://www.dovepress.com/dietary-patterns-in-relation-to-hepatic-fibrosis-among-patients-with-n-peer-reviewed-article-DMSO |
| work_keys_str_mv | AT soleimanid dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease AT ranjbarg dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease AT rezvanir dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease AT goshayeshil dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease AT razmpourf dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease AT nematym dietarypatternsinrelationtohepaticfibrosisamongpatientswithnonalcoholicfattyliverdisease |