Origin and evolution of protein fold designs inferred from phylogenomic analysis of CATH domain structures in proteomes.

Origin and evolution of protein fold designs inferred from phylogenomic analysis of CATH domain structures in proteomes.

The spatial arrangements of secondary structures in proteins, irrespective of their connectivity, depict the overall shape and organization of protein domains. These features have been used in the CATH and SCOP classifications to hierarchically partition fold space and define the architectural make...

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Bibliographic Details
Main Authors: Syed Abbas Bukhari, Gustavo Caetano-Anollés
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23555236/pdf/?tool=EBI

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