Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture

Zoonotic diseases are a group of infectious diseases that are transmitted naturally from animals to humans. <i>L. garvieae</i> is a Gram-positive bacterium which is present in the aquaculture of freshwater and marine fish. Some isolated cases of infection have been described, considering...

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Main Authors: Miguel Mayo-Yáñez, Lucía González-Torres
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Zoonotic Diseases
Subjects:
Online Access:https://www.mdpi.com/2813-0227/3/1/1
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author Miguel Mayo-Yáñez
Lucía González-Torres
author_facet Miguel Mayo-Yáñez
Lucía González-Torres
author_sort Miguel Mayo-Yáñez
collection DOAJ
description Zoonotic diseases are a group of infectious diseases that are transmitted naturally from animals to humans. <i>L. garvieae</i> is a Gram-positive bacterium which is present in the aquaculture of freshwater and marine fish. Some isolated cases of infection have been described, considering it an opportunistic agent in immunosuppressed patients. The most recent appearance of severe infections in immunocompetent patients or colonizing cardiac prostheses has set off the alarms. This manuscript presents the first two patients with recurrent tonsillitis due to <i>L. garvieae.</i> A 15-year-old male and an 8-year-old male had recurrent tonsillitis with more than three episodes per year. A culture of tonsillar exudate in both cases showed growth of <i>L. garvieae</i> with an antibiogram showing multi-resistance to antibiotics. Given the parents’ wish not to carry out surgery, an autovaccine regimen with lysed bacteria was proposed with good evolution and remission of tonsillitis episodes in both cases. The oral autovaccine produces an immunomodulatory effect and could be a therapeutic weapon in the prevention of this zoonosis. Further studies are needed to determine the importance of foodborne transmission in human <i>L. garvieae</i> infections and to find suitable treatments for this wide range of infections.
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spelling doaj.art-9ce5973b0f2144c3b0e15174d592283f2023-03-28T15:08:48ZengMDPI AGZoonotic Diseases2813-02272023-01-01311510.3390/zoonoticdis3010001Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from AquacultureMiguel Mayo-Yáñez0Lucía González-Torres1Otorhinolaryngology—Head and Neck Surgery Department, Complexo Hospitalario Universitario A Coruña (CHUAC), 15006 A Coruña, Galicia, SpainPediatrics Department, Complexo Hospitalario Universitario A Coruña (CHUAC), 15006 A Coruña, Galicia, SpainZoonotic diseases are a group of infectious diseases that are transmitted naturally from animals to humans. <i>L. garvieae</i> is a Gram-positive bacterium which is present in the aquaculture of freshwater and marine fish. Some isolated cases of infection have been described, considering it an opportunistic agent in immunosuppressed patients. The most recent appearance of severe infections in immunocompetent patients or colonizing cardiac prostheses has set off the alarms. This manuscript presents the first two patients with recurrent tonsillitis due to <i>L. garvieae.</i> A 15-year-old male and an 8-year-old male had recurrent tonsillitis with more than three episodes per year. A culture of tonsillar exudate in both cases showed growth of <i>L. garvieae</i> with an antibiogram showing multi-resistance to antibiotics. Given the parents’ wish not to carry out surgery, an autovaccine regimen with lysed bacteria was proposed with good evolution and remission of tonsillitis episodes in both cases. The oral autovaccine produces an immunomodulatory effect and could be a therapeutic weapon in the prevention of this zoonosis. Further studies are needed to determine the importance of foodborne transmission in human <i>L. garvieae</i> infections and to find suitable treatments for this wide range of infections.https://www.mdpi.com/2813-0227/3/1/1zoonotic diseasesmicrobiologyinfectious diseasestonsillitisotolaryngologypediatric
spellingShingle Miguel Mayo-Yáñez
Lucía González-Torres
Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
Zoonotic Diseases
zoonotic diseases
microbiology
infectious diseases
tonsillitis
otolaryngology
pediatric
title Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
title_full Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
title_fullStr Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
title_full_unstemmed Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
title_short Recurrent Penicillin-Resistant Tonsillitis Due to <i>Lactococcus garvieae</i>, a New Zoonosis from Aquaculture
title_sort recurrent penicillin resistant tonsillitis due to i lactococcus garvieae i a new zoonosis from aquaculture
topic zoonotic diseases
microbiology
infectious diseases
tonsillitis
otolaryngology
pediatric
url https://www.mdpi.com/2813-0227/3/1/1
work_keys_str_mv AT miguelmayoyanez recurrentpenicillinresistanttonsillitisduetoilactococcusgarvieaeianewzoonosisfromaquaculture
AT luciagonzaleztorres recurrentpenicillinresistanttonsillitisduetoilactococcusgarvieaeianewzoonosisfromaquaculture