MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders

The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal...

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Main Author: Moyra Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.577710/full
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author Moyra Smith
author_facet Moyra Smith
author_sort Moyra Smith
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description The growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in neurodevelopmental, cognitive, and behavioral disorders.
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spelling doaj.art-9ceb7673f3c6454089ae59ddfd2d874d2022-12-21T23:10:59ZengFrontiers Media S.A.Frontiers in Molecular Biosciences2296-889X2020-09-01710.3389/fmolb.2020.577710577710MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral DisordersMoyra SmithThe growth of expertise in molecular techniques, their application to clinical evaluations, and the establishment of databases with molecular genetic information has led to greater insights into the roles of molecular processes related to gene expression in neurodevelopment and functioning. The goal of this review is to examine new insights into messenger RNA transcription, translation, and cellular protein synthesis and the relevance of genetically determined alterations in these processes in neurodevelopmental, cognitive, and behavioral disorders.https://www.frontiersin.org/article/10.3389/fmolb.2020.577710/fulltranscriptiontranslationenhancerschromatincognitionautism
spellingShingle Moyra Smith
MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
Frontiers in Molecular Biosciences
transcription
translation
enhancers
chromatin
cognition
autism
title MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_full MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_fullStr MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_full_unstemmed MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_short MRNA Transcription, Translation, and Defects in Developmental Cognitive and Behavioral Disorders
title_sort mrna transcription translation and defects in developmental cognitive and behavioral disorders
topic transcription
translation
enhancers
chromatin
cognition
autism
url https://www.frontiersin.org/article/10.3389/fmolb.2020.577710/full
work_keys_str_mv AT moyrasmith mrnatranscriptiontranslationanddefectsindevelopmentalcognitiveandbehavioraldisorders