LTβR Signaling Controls Lymphatic Migration of Immune Cells

LTβR Signaling Controls Lymphatic Migration of Immune Cells

The pleiotropic functions of lymphotoxin (LT)β receptor (LTβR) signaling are linked to the control of secondary lymphoid organ development and structural maintenance, inflammatory or autoimmune disorders, and carcinogenesis. Recently, LTβR signaling in endothelial cells has been revealed to regulate...

Full description

Bibliographic Details
Main Authors:	Wenji Piao, Vivek Kasinath, Vikas Saxena, Ram Lakhan, Jegan Iyyathurai, Jonathan S. Bromberg
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Series:	Cells
Subjects:	lymphotoxin lymphotoxin β receptor signaling Treg migration non-canonical nuclear factor κB pathway lymphatic endothelial cells
Online Access:	https://www.mdpi.com/2073-4409/10/4/747

Similar Items

Deletion of lymphotoxin-β receptor (LTβR) protects against acute kidney injury by PPARα pathway
by: Zufeng Wang, et al.
Published: (2024-12-01)

LTβR-RelB signaling in intestinal epithelial cells protects from chemotherapy-induced mucosal damage
by: Qiangxing Chen, et al.
Published: (2024-05-01)

There exists only one tumor necrosis factor
by: S. A. Nedospasov
Published: (2021-01-01)

LTα, TNF, and ILC3 in Peyer’s Patch Organogenesis
by: Violetta S. Gogoleva, et al.
Published: (2022-06-01)

Increased Thymic B Cells but Maintenance of ThymicStructure, T Cell Differentiation and Negative Selectionin Lymphotoxin-α and TNF Gene-Targeted Mice
by: Adrian P. Grech, et al.
Published: (2000-01-01)

Inflammation due to ocular surface homeostasis imbalance caused by pterygia: tear lymphotoxin-alpha study and a literature review
by: Xie Fang, et al.
Published: (2024-06-01)

Role of lymphotoxin alpha as a new molecular biomarker in revolutionizing tear diagnostic testing for dry eye disease
by: Chao-Ran Li
Published: (2023-11-01)

Induction of Germinal Centers by MMTV EncodedSuperantigen on B Cells
by: W. J. Simmons, et al.
Published: (2001-01-01)

TNF Decoy Receptors Encoded by Poxviruses
by: Francisco Javier Alvarez-de Miranda, et al.
Published: (2021-08-01)

CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells
by: Neda Haghayegh Jahromi, et al.
Published: (2024-02-01)

Dissecting the role of single nucleotide polymorphism of lymphotoxin beta gene during pig domestication using bioinformatic and experimental approaches
by: R. B. Aitnazarov, et al.
Published: (2016-01-01)

Administration of RANKL boosts thymic regeneration upon bone marrow transplantation
by: Noella Lopes, et al.
Published: (2017-04-01)

Loss of Lymphotoxin Alpha-Expressing Memory B Cells Correlates with Metastasis of Human Primary Melanoma
by: Franziska Werner, et al.
Published: (2021-07-01)

The role of lymphatic endothelial cell metabolism in lymphangiogenesis and disease
by: Summer Simeroth, et al.
Published: (2024-05-01)

Pannexin1 deletion in lymphatic endothelium affects lymphatic function in a sex‐dependent manner
by: Avigail Ehrlich, et al.
Published: (2024-08-01)

Mechanisms and Clinical Significance of Tumor Lymphatic Invasion
by: Noriki Fujimoto, et al.
Published: (2021-09-01)

Advances in lymphatic metastasis of non-small cell lung cancer
by: Xiaofei Zhang, et al.
Published: (2024-04-01)

Lymphangiogenic responses of lymphatic endothelial cells to steady direct-current electric fields
by: Linbo Guan, et al.
Published: (2023-12-01)

Lymphatic Endothelial Markers and Tumor Lymphangiogenesis Assessment in Human Breast Cancer
by: Jia-Mei Chen, et al.
Published: (2021-12-01)

Hyperoxia Disrupts Lung Lymphatic Homeostasis in Neonatal Mice
by: Nithyapriya Shankar, et al.
Published: (2023-03-01)

On the unlocked secrets of the lymphatics and lymphatic circulation
by: Giancarlo Pansini
Published: (2024-01-01)

Enhanced meningeal lymphatic drainage ameliorates lipopolysaccharide-induced brain injury in aged mice
by: Hongquan Dong, et al.
Published: (2024-01-01)

Lymphatic and blood vessels in parathyroid tumors: Immunohistochemical study with LYVE-1 and von Willebrand factor
by: Tatsuo Tomita
Published: (2024-08-01)

Advances in the Understanding of ocular and nasal lymphatics
by: Min Yan, et al.
Published: (2025-03-01)

Lymphatic Senescence: Current Updates and Perspectives
by: Sebastian Lucio Filelfi, et al.
Published: (2021-04-01)

Dysregulation of Lymphatic Endothelial VEGFR3 Signaling in Disease
by: Kevin Kuonqui, et al.
Published: (2023-12-01)

The Lymphatic Endothelial Cell Secretome Inhibits Osteoblast Differentiation and Bone Formation
by: Ernesto Solorzano, et al.
Published: (2023-10-01)

ULTRASTRUCTURAL ORGANIZATION OF THE LYMPHATIC CAPILLARIES IN CONJUNCTIVA AND THE LYMPHATIC CHANNELS IN HUMAN CHOROID
by: S. R. Nogovitsina, et al.
Published: (2019-06-01)

Microvesicles derived from dermal myofibroblasts modify the integrity of the blood and lymphatic barriers using distinct endocytosis pathways
by: Syrine Arif, et al.
Published: (2024-05-01)

Lung lymphatic endothelial cells undergo inflammatory and prothrombotic changes in a model of chronic obstructive pulmonary disease
by: Anjali Trivedi, et al.
Published: (2024-02-01)

Lymphatic System and Procedures /
by: Craig, Winifred, author 647965, et al.
Published: (2012)

Expression of molecular lymphatic markers in human choroid
by: S. R. Nogovitsina
Published: (2016-09-01)

Impaired meningeal lymphatic drainage in Listeria monocytogenes infection
by: Jian Feng, et al.
Published: (2024-04-01)

Lymphatic Endothelial-to-Myofibroblast Transition: A Potential New Mechanism Underlying Skin Fibrosis in Systemic Sclerosis
by: Irene Rosa, et al.
Published: (2023-09-01)

Interleukin-7-based identification of liver lymphatic endothelial cells reveals their unique structural features
by: Yilin Yang, et al.
Published: (2024-07-01)

Pulmonary lymphatic function and its research progress in pulmonary diseases
by: Kang Xuya, et al.
Published: (2023-06-01)

Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes
by: Eliane Sibler, et al.
Published: (2021-06-01)

Commentary: The central lymphatic drainage in pharmacological, surgical and physical therapies of Alzheimer's disease
by: Lixuan Ren, et al.
Published: (2024-07-01)

Occurrence of Lymphangiogenesis in Peripheral Nerve Autografts Contrasts Schwann Cell-Induced Apoptosis of Lymphatic Endothelial Cells In Vitro
by: Carina Hromada, et al.
Published: (2022-06-01)

The Transcription Factor SOX18 Inhibitor Small Molecule 4 Is a Potential Treatment of Cancer‐Induced Lymphatic Metastasis and Lymphangiosarcoma
by: Katja K. Koll, et al.
Published: (2025-01-01)