Immunological basis of vaccination
The basic mechanisms of body defences against infectious diseases are both non- specific and specific immune systems. Non- specific immunity refers to mechanism of protection that do not require specific recognition of antigen, but that increase the protection afforded by specific immune mechanisms....
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| Format: | Article |
| Language: | English |
| Published: |
Indonesian Pediatric Society Publishing House
2016-09-01
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| Series: | Paediatrica Indonesiana |
| Subjects: | |
| Online Access: | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/684 |
| _version_ | 1818827531169562624 |
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| author | Ariyanto Harsono |
| author_facet | Ariyanto Harsono |
| author_sort | Ariyanto Harsono |
| collection | DOAJ |
| description | The basic mechanisms of body defences
against infectious diseases are both non-
specific and specific immune systems. Non-
specific immunity refers to mechanism of
protection that do not require specific recognition of
antigen, but that increase the protection afforded by
specific immune mechanisms. Non-specific immune
mechanisms include phagocytes, acute inflammatory
responses, type-1 interferon, and tumour necrosing
factor. Specific immunity consists of mechanisms of
protection that require specific recognition of antigen.
This immunity is highly specific, inducible,
discriminatory and unforgotten T lymphocyte-
dependent response. Normal specific immunity
operates under Major Histocompatibility Complex
restriction. It is the ability of this immune system to
refine its antigen recognition domains and establish
immunological memory that underlies the success of
active vaccination. |
| first_indexed | 2024-12-19T00:45:02Z |
| format | Article |
| id | doaj.art-9ced57f2aca1442cb0c8b8d5189e51de |
| institution | Directory Open Access Journal |
| issn | 0030-9311 2338-476X |
| language | English |
| last_indexed | 2024-12-19T00:45:02Z |
| publishDate | 2016-09-01 |
| publisher | Indonesian Pediatric Society Publishing House |
| record_format | Article |
| series | Paediatrica Indonesiana |
| spelling | doaj.art-9ced57f2aca1442cb0c8b8d5189e51de2022-12-21T20:44:19ZengIndonesian Pediatric Society Publishing HousePaediatrica Indonesiana0030-93112338-476X2016-09-01435151710.14238/pi43.5.2003.151-7550Immunological basis of vaccinationAriyanto HarsonoThe basic mechanisms of body defences against infectious diseases are both non- specific and specific immune systems. Non- specific immunity refers to mechanism of protection that do not require specific recognition of antigen, but that increase the protection afforded by specific immune mechanisms. Non-specific immune mechanisms include phagocytes, acute inflammatory responses, type-1 interferon, and tumour necrosing factor. Specific immunity consists of mechanisms of protection that require specific recognition of antigen. This immunity is highly specific, inducible, discriminatory and unforgotten T lymphocyte- dependent response. Normal specific immunity operates under Major Histocompatibility Complex restriction. It is the ability of this immune system to refine its antigen recognition domains and establish immunological memory that underlies the success of active vaccination.https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/684Immunological basisvaccination |
| spellingShingle | Ariyanto Harsono Immunological basis of vaccination Paediatrica Indonesiana Immunological basis vaccination |
| title | Immunological basis of vaccination |
| title_full | Immunological basis of vaccination |
| title_fullStr | Immunological basis of vaccination |
| title_full_unstemmed | Immunological basis of vaccination |
| title_short | Immunological basis of vaccination |
| title_sort | immunological basis of vaccination |
| topic | Immunological basis vaccination |
| url | https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/684 |
| work_keys_str_mv | AT ariyantoharsono immunologicalbasisofvaccination |