Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer
The approaches of InterCriteria Analysis and Correlation Analysis are applied to a dataset of calorimetric and statistical parameters obtained from blood plasma proteome thermograms of colorectal cancer patients. The analysis was performed for four individual predefined subsets of calorimetric profi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Bulgarian Academy of Sciences
2016-03-01
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| Series: | International Journal Bioautomation |
| Subjects: | |
| Online Access: | http://www.biomed.bas.bg/bioautomation/2016/vol_20.1/files/20.1_09.pdf |
| _version_ | 1811322796837437440 |
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| author | Svetla Todinova Deyan Mavrov Sashka Krumova Pencho Marinov Vassia Atanassova Krassimir Atanassov Stefka G. Taneva |
| author_facet | Svetla Todinova Deyan Mavrov Sashka Krumova Pencho Marinov Vassia Atanassova Krassimir Atanassov Stefka G. Taneva |
| author_sort | Svetla Todinova |
| collection | DOAJ |
| description | The approaches of InterCriteria Analysis and Correlation Analysis are applied to a dataset of calorimetric and statistical parameters obtained from blood plasma proteome thermograms of colorectal cancer patients. The analysis was performed for four individual predefined subsets of calorimetric profiles. Specific interrelations between the studied criteria were identified that were found to differ among the different calorimetric subsets. For three of the subsets the enthalpy of the thermal profiles was in strong consonance with the excess heat capacity of the immunoglobulins assigned thermal transition. For the calorimetric subsets that differed most from the control healthy set a strong interrelation between the excess heat capacities of the main plasma proteins (albumin and immunoglobulins) was additionally evident. Our results demonstrate that these mathematical approaches can complement the analysis of calorimetric datasets generated for a variety of diseases. |
| first_indexed | 2024-04-13T13:42:44Z |
| format | Article |
| id | doaj.art-9cf058eb990d4a629dac58db67dc5a73 |
| institution | Directory Open Access Journal |
| issn | 1314-1902 1314-2321 |
| language | English |
| last_indexed | 2024-04-13T13:42:44Z |
| publishDate | 2016-03-01 |
| publisher | Bulgarian Academy of Sciences |
| record_format | Article |
| series | International Journal Bioautomation |
| spelling | doaj.art-9cf058eb990d4a629dac58db67dc5a732022-12-22T02:44:35ZengBulgarian Academy of SciencesInternational Journal Bioautomation1314-19021314-23212016-03-01201115124Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal CancerSvetla Todinova0Deyan MavrovSashka KrumovaPencho MarinovVassia AtanassovaKrassimir AtanassovStefka G. TanevaInstitute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Acad. G. Bonchev Str., Bl. 21 and Bl. 105, 1113 Sofia, BulgariaThe approaches of InterCriteria Analysis and Correlation Analysis are applied to a dataset of calorimetric and statistical parameters obtained from blood plasma proteome thermograms of colorectal cancer patients. The analysis was performed for four individual predefined subsets of calorimetric profiles. Specific interrelations between the studied criteria were identified that were found to differ among the different calorimetric subsets. For three of the subsets the enthalpy of the thermal profiles was in strong consonance with the excess heat capacity of the immunoglobulins assigned thermal transition. For the calorimetric subsets that differed most from the control healthy set a strong interrelation between the excess heat capacities of the main plasma proteins (albumin and immunoglobulins) was additionally evident. Our results demonstrate that these mathematical approaches can complement the analysis of calorimetric datasets generated for a variety of diseases.http://www.biomed.bas.bg/bioautomation/2016/vol_20.1/files/20.1_09.pdfInterCriteria analysisCorrelation аnalysisDifferential scanning calorimetryColorectal cancer |
| spellingShingle | Svetla Todinova Deyan Mavrov Sashka Krumova Pencho Marinov Vassia Atanassova Krassimir Atanassov Stefka G. Taneva Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer International Journal Bioautomation InterCriteria analysis Correlation аnalysis Differential scanning calorimetry Colorectal cancer |
| title | Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer |
| title_full | Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer |
| title_fullStr | Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer |
| title_full_unstemmed | Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer |
| title_short | Blood Plasma Thermograms Dataset Analysisby Means of InterCriteria and Correlation Analyses for the Case of Colorectal Cancer |
| title_sort | blood plasma thermograms dataset analysisby means of intercriteria and correlation analyses for the case of colorectal cancer |
| topic | InterCriteria analysis Correlation аnalysis Differential scanning calorimetry Colorectal cancer |
| url | http://www.biomed.bas.bg/bioautomation/2016/vol_20.1/files/20.1_09.pdf |
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