Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand
More than half of newly diagnosed HIV-infected patients enter to care with a low CD4 count. A retrospective cohort study was conducted among newly diagnosed HIV-infected adults who were hospitalized. Of 148 patients, median (interquartile range [IQR]) age was 39.3 (30.5-47.1) years and 114 (77%) pat...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-04-01
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| Series: | Journal of the International Association of Providers of AIDS Care |
| Online Access: | https://doi.org/10.1177/2325958220919266 |
| _version_ | 1818109733022728192 |
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| author | Sukonthip Chanto MD Sasisopin Kiertiburanakul MD, MHS |
| author_facet | Sukonthip Chanto MD Sasisopin Kiertiburanakul MD, MHS |
| author_sort | Sukonthip Chanto MD |
| collection | DOAJ |
| description | More than half of newly diagnosed HIV-infected patients enter to care with a low CD4 count. A retrospective cohort study was conducted among newly diagnosed HIV-infected adults who were hospitalized. Of 148 patients, median (interquartile range [IQR]) age was 39.3 (30.5-47.1) years and 114 (77%) patients were male. Baseline median (IQR) CD4 count was 79 (24-218) cells/mm 3 . The median (IQR) length of hospital stay was 8 (4-16) days. Half of the patients were hospitalized with AIDS-defining illness (ADI). Common opportunistic infections were Pneumocystis jirovecii pneumonia (20.3%) and tuberculosis (18.9%). CD4 count was statistically significantly associated with hospitalization with ADI (odds ratio: 0.85, per 10 cells/mm 3 increased; 95% confidence interval: 0.80-0.90). The mortality was 5.4%. In conclusion, half of newly diagnosed Thai HIV-infected patients were hospitalized with ADI. Early detection of HIV infection leading to early antiretroviral therapy initiation and prevention of serious complications is essential. |
| first_indexed | 2024-12-11T02:35:56Z |
| format | Article |
| id | doaj.art-9cf2d8539fe84a3e81344226cecec5b3 |
| institution | Directory Open Access Journal |
| issn | 2325-9582 |
| language | English |
| last_indexed | 2024-12-11T02:35:56Z |
| publishDate | 2020-04-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of the International Association of Providers of AIDS Care |
| spelling | doaj.art-9cf2d8539fe84a3e81344226cecec5b32022-12-22T01:23:43ZengSAGE PublishingJournal of the International Association of Providers of AIDS Care2325-95822020-04-011910.1177/2325958220919266Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in ThailandSukonthip Chanto MD0Sasisopin Kiertiburanakul MD, MHS1 Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandMore than half of newly diagnosed HIV-infected patients enter to care with a low CD4 count. A retrospective cohort study was conducted among newly diagnosed HIV-infected adults who were hospitalized. Of 148 patients, median (interquartile range [IQR]) age was 39.3 (30.5-47.1) years and 114 (77%) patients were male. Baseline median (IQR) CD4 count was 79 (24-218) cells/mm 3 . The median (IQR) length of hospital stay was 8 (4-16) days. Half of the patients were hospitalized with AIDS-defining illness (ADI). Common opportunistic infections were Pneumocystis jirovecii pneumonia (20.3%) and tuberculosis (18.9%). CD4 count was statistically significantly associated with hospitalization with ADI (odds ratio: 0.85, per 10 cells/mm 3 increased; 95% confidence interval: 0.80-0.90). The mortality was 5.4%. In conclusion, half of newly diagnosed Thai HIV-infected patients were hospitalized with ADI. Early detection of HIV infection leading to early antiretroviral therapy initiation and prevention of serious complications is essential.https://doi.org/10.1177/2325958220919266 |
| spellingShingle | Sukonthip Chanto MD Sasisopin Kiertiburanakul MD, MHS Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand Journal of the International Association of Providers of AIDS Care |
| title | Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand |
| title_full | Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand |
| title_fullStr | Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand |
| title_full_unstemmed | Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand |
| title_short | Causes of Hospitalization and Death among Newly Diagnosed HIV-Infected Adults in Thailand |
| title_sort | causes of hospitalization and death among newly diagnosed hiv infected adults in thailand |
| url | https://doi.org/10.1177/2325958220919266 |
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