Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia

Double-Blind Clinical Trial of Arginine Supplementation in the Treatment of Adult Patients with Sickle Cell Anaemia

Background. Sickle cell anaemia (SCA) is the most prevalent monogenic disease in Brazil. In SCA, haemoglobin S (HbS) is formed, which modifies red blood cell morphology. Intravascular haemolysis occurs, in which free Hb and free radicals degrade nitric oxide (NO) and release arginase, which reduces...

Полное описание

Библиографические подробности
Главные авторы:	Renata M. N. Eleutério, Francisco O. Nascimento, Tamara G. Araújo, Marilena F. Castro, Tarcísio P. Almeida Filho, Pedro A. Maia Filho, José Eleutério, Darcielle B. D. Elias, Romélia P. G. Lemes
Формат:	Статья
Язык:	English
Опубликовано:	Wiley 2019-01-01
Серии:	Advances in Hematology
Online-ссылка:	http://dx.doi.org/10.1155/2019/4397150

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