Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention

Exosomes from GM-CSF expressing embryonic stem cells are an effective prophylactic vaccine for cancer prevention

The antigenic similarity between embryos and tumors has raised the idea of using embryonic material as a preventative vaccine against neoplastic disease. Indeed, we have previously reported that a vaccine comprises allogeneic murine embryonic stem cells (ESCs) and murine fibroblasts expressing GM-CS...

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Bibliographic Details
Main Authors: Kavitha Yaddanapudi, Shuhan Meng, Aaron G. Whitt, Numan Al Rayyan, Jamaal Richie, Allison Tu, John W. Eaton, Chi Li
Format: Article
Language:English
Published: Taylor & Francis Group 2019-03-01
Series:OncoImmunology
Subjects:
cancer
embryonic stem cells
exosomes
prophylactic vaccine
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1561119

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