Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis

Abstract: We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the treatme...

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Main Authors: Xiaolin Bu, Juan Fan, Xiaoli Hu, Xinling Bi, Bin Peng, Denghai Zhang
Format: Article
Language:English
Published: Sociedade Brasileira de Dermatologia 2017-08-01
Series:Anais Brasileiros de Dermatologia
Subjects:
Online Access:http://www.scielo.br/pdf/abd/v92n4/0365-0596-abd-92-04-0556.pdf
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author Xiaolin Bu
Juan Fan
Xiaoli Hu
Xinling Bi
Bin Peng
Denghai Zhang
author_facet Xiaolin Bu
Juan Fan
Xiaoli Hu
Xinling Bi
Bin Peng
Denghai Zhang
author_sort Xiaolin Bu
collection DOAJ
description Abstract: We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the treatment, but he developed aggressive hyperkeratotic lesions with rapid progression after using tripterygium glycoside. He was repeatedly diagnosed with eczema, but treatment failed to achieve efficacy. Interestingly, a microscopic examination of the lesions revealed numerous scabies mites and eggs. Thus, we confirmed the diagnosis of Norwegian scabies infection. Treated with crotamiton 10% cream and 10% sulfur ointment for one month, the patient's clinical symptoms disappeared.
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spelling doaj.art-9cf535b6bc6641898173be6c71a8cad82022-12-21T21:23:54ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962017-08-0192455655810.1590/abd1806-4841.20174946Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritisXiaolin BuJuan FanXiaoli HuXinling BiBin PengDenghai ZhangAbstract: We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the treatment, but he developed aggressive hyperkeratotic lesions with rapid progression after using tripterygium glycoside. He was repeatedly diagnosed with eczema, but treatment failed to achieve efficacy. Interestingly, a microscopic examination of the lesions revealed numerous scabies mites and eggs. Thus, we confirmed the diagnosis of Norwegian scabies infection. Treated with crotamiton 10% cream and 10% sulfur ointment for one month, the patient's clinical symptoms disappeared.http://www.scielo.br/pdf/abd/v92n4/0365-0596-abd-92-04-0556.pdfArthritis, rheumatoidHerbal medicineImmunosuppressionSarcoptes scabiei
spellingShingle Xiaolin Bu
Juan Fan
Xiaoli Hu
Xinling Bi
Bin Peng
Denghai Zhang
Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
Anais Brasileiros de Dermatologia
Arthritis, rheumatoid
Herbal medicine
Immunosuppression
Sarcoptes scabiei
title Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
title_full Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
title_fullStr Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
title_full_unstemmed Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
title_short Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis
title_sort norwegian scabies in a patient treated with tripterygium glycoside for rheumatoid arthritis
topic Arthritis, rheumatoid
Herbal medicine
Immunosuppression
Sarcoptes scabiei
url http://www.scielo.br/pdf/abd/v92n4/0365-0596-abd-92-04-0556.pdf
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