Mir-22-3p Inhibits Arterial Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia by Targeting HMGB1 in Arteriosclerosis Obliterans

Mir-22-3p Inhibits Arterial Smooth Muscle Cell Proliferation and Migration and Neointimal Hyperplasia by Targeting HMGB1 in Arteriosclerosis Obliterans

Background: Aberrant vascular smooth muscle cell (VSMC) proliferation and migration contribute to the development of vascular pathologies, such as atherosclerosis and post-angioplasty restenosis. The aim of this study was to determine whether miR-22-3p plays a role in regulating human artery vascula...

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Bibliographic Details
Main Authors: Shui-chuan Huang, Mian Wang, Wei-bin Wu, Rui Wang, Jin Cui, Wen Li, Zi-lun Li, Shen-ming Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mirna-22-3p
Arteriosclerosis
Human arterial smooth muscle cell
Proliferation
Migration
Neointimal hyperplasia
HMGB1
Online Access:http://www.karger.com/Article/FullText/480212

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