Coming of Age: CD96 Emerges as Modulator of Immune Responses

Coming of Age: CD96 Emerges as Modulator of Immune Responses

CD96 represents a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD96 is expressed mainly by cells of hematopoietic origin, in particular on T and NK cells. Upon interaction with CD155 present on target cells, CD96 was found to inhibit mouse NK cells, and absence of t...

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Bibliographic Details
Main Authors: Hristo Georgiev, Inga Ravens, Georgia Papadogianni, Günter Bernhardt
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
CD96
immunoglobulin superfamily
CD155
CD226
TIGIT
NK cells
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.01072/full

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