Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report
Benign Peripheral Nerve Sheath Tumours (BPNSTs) are traditionally classified into schwannoma, neurofibroma and perinurioma. Due to advances in molecular techniques, hybrid BPNSTs containing more than one histologic types have been documented. Recent studies have demonstrated their frequent associa...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2015-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/6600/15723_CE[Ra]_F(P)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
| _version_ | 1819054763075960832 |
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| author | Kishori Moni Panda Naik Reena |
| author_facet | Kishori Moni Panda Naik Reena |
| author_sort | Kishori Moni Panda |
| collection | DOAJ |
| description | Benign Peripheral Nerve Sheath Tumours (BPNSTs) are traditionally classified into schwannoma, neurofibroma and perinurioma. Due to
advances in molecular techniques, hybrid BPNSTs containing more than one histologic types have been documented. Recent studies
have demonstrated their frequent association with inherited syndromes like schwannomatosis and neurofibromatosis. Intraneural
variant of hybrid neurofibroma/schwannoma is yet to be described. Here we report such a case in a 30-year-old male, who presented
with a scalp swelling and histology showed intraneural neurofibromatous tumour admixed with schwannoma-like nodules. IHC
(immunohistochemistry) showed variable S100 staining in neurofibromatous areas, diffuse S100 staining in schwannoma-like areas and
negative EMA staining in the tumour. |
| first_indexed | 2024-12-21T12:56:47Z |
| format | Article |
| id | doaj.art-9d0433a657774dd3a57b4c6520c51ad5 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T12:56:47Z |
| publishDate | 2015-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-9d0433a657774dd3a57b4c6520c51ad52022-12-21T19:03:18ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-10-01910ED05ED0610.7860/JCDR/2015/15723.6600Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case ReportKishori Moni Panda0Naik Reena1Professor and HOD, Department of Pathology, Government Medical College (LSLAMMC), Raigarh, Chhattishgarh, India.Demonstrator, Department of Pathology, Government Medical College (LSLAMMC), Raigarh, Chhattishgarh, India.Benign Peripheral Nerve Sheath Tumours (BPNSTs) are traditionally classified into schwannoma, neurofibroma and perinurioma. Due to advances in molecular techniques, hybrid BPNSTs containing more than one histologic types have been documented. Recent studies have demonstrated their frequent association with inherited syndromes like schwannomatosis and neurofibromatosis. Intraneural variant of hybrid neurofibroma/schwannoma is yet to be described. Here we report such a case in a 30-year-old male, who presented with a scalp swelling and histology showed intraneural neurofibromatous tumour admixed with schwannoma-like nodules. IHC (immunohistochemistry) showed variable S100 staining in neurofibromatous areas, diffuse S100 staining in schwannoma-like areas and negative EMA staining in the tumour.https://jcdr.net/articles/PDF/6600/15723_CE[Ra]_F(P)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdfihcpathologybpnst |
| spellingShingle | Kishori Moni Panda Naik Reena Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report Journal of Clinical and Diagnostic Research ihc pathology bpnst |
| title | Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report |
| title_full | Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report |
| title_fullStr | Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report |
| title_full_unstemmed | Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report |
| title_short | Intraneural Hybrid Neurofibroma/ Schwannoma In Scalp: A Case Report |
| title_sort | intraneural hybrid neurofibroma schwannoma in scalp a case report |
| topic | ihc pathology bpnst |
| url | https://jcdr.net/articles/PDF/6600/15723_CE[Ra]_F(P)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
| work_keys_str_mv | AT kishorimonipanda intraneuralhybridneurofibromaschwannomainscalpacasereport AT naikreena intraneuralhybridneurofibromaschwannomainscalpacasereport |