Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy

Objective. To evaluate morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus (DM2) and diabetic cardiovascular autonomic neuropathy (CAN). Materials and methods. A total of 139 patients with DM2 and hypertension (mean age: 53.1?4.9 years; mean d...

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Main Authors: Irina Arkad'evna Bondar', Alexander Aristarkhovich Demin, Olesya Yur'evna Shabel'nikova
Format: Article
Language:English
Published: Endocrinology Research Centre 2014-07-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/6407
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author Irina Arkad'evna Bondar'
Alexander Aristarkhovich Demin
Olesya Yur'evna Shabel'nikova
author_facet Irina Arkad'evna Bondar'
Alexander Aristarkhovich Demin
Olesya Yur'evna Shabel'nikova
author_sort Irina Arkad'evna Bondar'
collection DOAJ
description Objective. To evaluate morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus (DM2) and diabetic cardiovascular autonomic neuropathy (CAN). Materials and methods. A total of 139 patients with DM2 and hypertension (mean age: 53.1?4.9 years; mean duration of hypertension: 9.7?7.8 years) were included in this study. Based on cardiovascular autonomic function test results (electrocardiography, heart rate variability) patients were divided into 2 groups as follows: Group 1 included 40 patients without CAN and Group 2 included 99 patients with CAN. The control group comprised 30 patients with hypertension and normal carbohydrate metabolism (mean age: 53.1?6.0 years; mean duration of hypertension: 10.9?8.5 years). All patients underwent ultrasonography of the heart and common carotid artery. Results. Group 2 patients showed a significant decrease in maximal transmitral flow velocity during early diastolic filling (0.61?0.12 m/s) and a decrease in maximal transmitral flow velocity during late diastolic filling (0.65?0.11 m/s) compared with Group 1 patients (0.66?0.09 m/s and 0.69?0.09 m/s, respectively, р
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spelling doaj.art-9d05dcc723d543c5931ac6f6ce7577b92024-03-20T11:47:59ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782014-07-01172414610.14341/DM2014241-466416Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathyIrina Arkad'evna Bondar'0Alexander Aristarkhovich Demin1Olesya Yur'evna Shabel'nikova2Novosibirsk State Medical University, NovosibirskNovosibirsk State Medical University, NovosibirskNovosibirsk State Regional Hospital, NovosibirskObjective. To evaluate morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus (DM2) and diabetic cardiovascular autonomic neuropathy (CAN). Materials and methods. A total of 139 patients with DM2 and hypertension (mean age: 53.1?4.9 years; mean duration of hypertension: 9.7?7.8 years) were included in this study. Based on cardiovascular autonomic function test results (electrocardiography, heart rate variability) patients were divided into 2 groups as follows: Group 1 included 40 patients without CAN and Group 2 included 99 patients with CAN. The control group comprised 30 patients with hypertension and normal carbohydrate metabolism (mean age: 53.1?6.0 years; mean duration of hypertension: 10.9?8.5 years). All patients underwent ultrasonography of the heart and common carotid artery. Results. Group 2 patients showed a significant decrease in maximal transmitral flow velocity during early diastolic filling (0.61?0.12 m/s) and a decrease in maximal transmitral flow velocity during late diastolic filling (0.65?0.11 m/s) compared with Group 1 patients (0.66?0.09 m/s and 0.69?0.09 m/s, respectively, рhttps://www.dia-endojournals.ru/jour/article/view/6407diabetes mellitusheartcardiovascular autonomic neuropathydeterminants
spellingShingle Irina Arkad'evna Bondar'
Alexander Aristarkhovich Demin
Olesya Yur'evna Shabel'nikova
Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
Сахарный диабет
diabetes mellitus
heart
cardiovascular autonomic neuropathy
determinants
title Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
title_full Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
title_fullStr Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
title_full_unstemmed Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
title_short Morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
title_sort morphological and functional parameters of the heart and vessels in patients with type 2 diabetes mellitus and cardiovascular autonomic neuropathy
topic diabetes mellitus
heart
cardiovascular autonomic neuropathy
determinants
url https://www.dia-endojournals.ru/jour/article/view/6407
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AT alexanderaristarkhovichdemin morphologicalandfunctionalparametersoftheheartandvesselsinpatientswithtype2diabetesmellitusandcardiovascularautonomicneuropathy
AT olesyayurevnashabelnikova morphologicalandfunctionalparametersoftheheartandvesselsinpatientswithtype2diabetesmellitusandcardiovascularautonomicneuropathy