Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV
Left ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysio...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-09-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043321003642 |
| _version_ | 1819114336971390976 |
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| author | Kok Hoe Chan, MD Amr Ramahi, MD Su Lin Lim, MD Eyad Ahmed, MD Addi Suleiman, MD Jihad Slim, MD Hamid S Shaaban, MD |
| author_facet | Kok Hoe Chan, MD Amr Ramahi, MD Su Lin Lim, MD Eyad Ahmed, MD Addi Suleiman, MD Jihad Slim, MD Hamid S Shaaban, MD |
| author_sort | Kok Hoe Chan, MD |
| collection | DOAJ |
| description | Left ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysiology remains uncertain; some studies have proposed chronic inflammation as the underlying etiology. Nonetheless, left ventricular thrombus is extremely rare among persons living with HIV with no known underlying cardiac disease. Herein, we report an unusual case of a 55-year-old homeless and heterosexual male with past medical history of HIV, who has mildly reduced left ventricular function and a nonmobile, medium size left ventricular thrombus. Patient was initially treated with therapeutic dose of enoxaparin, and subsequently developed acute embolic occlusion of right femoral artery that lead to an above knee amputation. To our knowledge, left ventricular thromboembolism complicated with acute embolic ischemia in persons living with HIV is extremely rare. The presenting case will definitely add to the current body of knowledge and will raise awareness among physicians, in recognizing the rare association between HIV and arterial thromboembolism. |
| first_indexed | 2024-12-22T04:43:41Z |
| format | Article |
| id | doaj.art-9d07927d6522414dab52063dc7d8f4e4 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-22T04:43:41Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-9d07927d6522414dab52063dc7d8f4e42022-12-21T18:38:39ZengElsevierRadiology Case Reports1930-04332021-09-0116924162420Left ventricular thrombus complicated by acute limb ischemia in a patient with HIVKok Hoe Chan, MD0Amr Ramahi, MD1Su Lin Lim, MD2Eyad Ahmed, MD3Addi Suleiman, MD4Jihad Slim, MD5Hamid S Shaaban, MD6Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USA; Corresponding author.Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USADepartment of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USADepartment of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USADepartment of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USA; Department of Cardiology, Saint Michael's Medical Centre, New York Medical College, NJ, USADepartment of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USA; Department of Infectious Disease, Saint Michael's Medical Centre, New York Medical College, NJ, USADepartment of Medical Education, Saint Michael's Medical Centre, New York Medical College, NJ, USA; Department of Hematology/Oncology, Saint Michael's Medical Centre, New York Medical College, NJ, USALeft ventricular thrombus typically occurs in patients with impaired left ventricular function such as aneurysm, dilated cardiomyopathy, or post-myocardial infarction. Untreated HIV infection is known to increase the risk of venous thromboembolism and cardiovascular disease. However, the pathophysiology remains uncertain; some studies have proposed chronic inflammation as the underlying etiology. Nonetheless, left ventricular thrombus is extremely rare among persons living with HIV with no known underlying cardiac disease. Herein, we report an unusual case of a 55-year-old homeless and heterosexual male with past medical history of HIV, who has mildly reduced left ventricular function and a nonmobile, medium size left ventricular thrombus. Patient was initially treated with therapeutic dose of enoxaparin, and subsequently developed acute embolic occlusion of right femoral artery that lead to an above knee amputation. To our knowledge, left ventricular thromboembolism complicated with acute embolic ischemia in persons living with HIV is extremely rare. The presenting case will definitely add to the current body of knowledge and will raise awareness among physicians, in recognizing the rare association between HIV and arterial thromboembolism.http://www.sciencedirect.com/science/article/pii/S1930043321003642LV thrombusHIVAIDSArterial embolus |
| spellingShingle | Kok Hoe Chan, MD Amr Ramahi, MD Su Lin Lim, MD Eyad Ahmed, MD Addi Suleiman, MD Jihad Slim, MD Hamid S Shaaban, MD Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV Radiology Case Reports LV thrombus HIV AIDS Arterial embolus |
| title | Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV |
| title_full | Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV |
| title_fullStr | Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV |
| title_full_unstemmed | Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV |
| title_short | Left ventricular thrombus complicated by acute limb ischemia in a patient with HIV |
| title_sort | left ventricular thrombus complicated by acute limb ischemia in a patient with hiv |
| topic | LV thrombus HIV AIDS Arterial embolus |
| url | http://www.sciencedirect.com/science/article/pii/S1930043321003642 |
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