Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018
Abstract Background Rubella is a vaccine-preventable contagious disease causing an estimated 100,000 children to be born with congenital rubella syndrome each year globally. Studies documented that 18 rubella outbreaks were occurred each year in Ethiopia. Yeka sub-city woreda 13 public health emerge...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-03-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-019-3873-y |
| _version_ | 1819266298051297280 |
|---|---|
| author | Getachew Dinede Abigiya Wondimagegnehu Fikre Enquselassie |
| author_facet | Getachew Dinede Abigiya Wondimagegnehu Fikre Enquselassie |
| author_sort | Getachew Dinede |
| collection | DOAJ |
| description | Abstract Background Rubella is a vaccine-preventable contagious disease causing an estimated 100,000 children to be born with congenital rubella syndrome each year globally. Studies documented that 18 rubella outbreaks were occurred each year in Ethiopia. Yeka sub-city woreda 13 public health emergency management office reported two measles suspected cases on 8 February, 2018. We investigated this outbreak to identify its etiology, describe the outbreak and implement control measures. Methods We described the outbreak using descriptive epidemiology. The study population was defined as students learning in the school where the outbreak occurred. Suspected rubella case was defined as student with generalized rash whereas confirmed case was suspected case tested positive for rubella IgM. Questionnaires, checklists and students record review were used to collect data. We searched for new cases in classes daily and excluded them from classes. The school environment was assessed and the outbreak was described in person and time. Results We identified 58 cases (median age: 4.6 years; IQR: 4–5 years) with six of them rubella IgM positive and 52 epidemiologically linked. The outbreak began on 8 February 2018 having multiple intermittent peaks during its course reaching its highest peak at 2 April, 2018 and ended on 20 April, 2018. Index cases were reported from two classes; however, cases were occurred in 13/15(86.67%) of the classes during the entire outbreak. Fifty five percent (32/58) and 45/58(77.59%) of the cases were females and 3–5 years children, respectively. Overall attack rate was 58/531(4.05%). Attack rate was higher in females 32/252 (12.7%) than in males 26/279 (9.32%), and higher 45/275(16.36%) in 3–5 years than those in 5–8 years 13/256(5.08%) children. Case fatality ratio was zero. All cases were vaccinated against measles but unvaccinated against rubella. Conclusions Attack rate was higher in females than in males and higher in 3–5 years than 5–8 years children. We recommended establishing rubella surveillance system, conducting sero-prevalence of rubella among child bearing age females and establishing CRS surveillance among young infants to provide evidence-based information for RCV introduction. It was also recommended to develop a national rubella surveillance guideline which aid to exclude rubella cases from schools during outbreak. |
| first_indexed | 2024-12-23T20:59:03Z |
| format | Article |
| id | doaj.art-9d09bb5f56c34246ab308ad9d467a224 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-23T20:59:03Z |
| publishDate | 2019-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-9d09bb5f56c34246ab308ad9d467a2242022-12-21T17:31:26ZengBMCBMC Infectious Diseases1471-23342019-03-011911710.1186/s12879-019-3873-yRubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018Getachew Dinede0Abigiya Wondimagegnehu1Fikre Enquselassie2Epidemiology Directorate, Ministry of AgricultureEpidemiology Unit, Department of Preventive Medicine, School of Public Health, Addis Ababa UniversityHead of Department of Preventive Medicine, School Of Public Health, Addis Ababa UniversityAbstract Background Rubella is a vaccine-preventable contagious disease causing an estimated 100,000 children to be born with congenital rubella syndrome each year globally. Studies documented that 18 rubella outbreaks were occurred each year in Ethiopia. Yeka sub-city woreda 13 public health emergency management office reported two measles suspected cases on 8 February, 2018. We investigated this outbreak to identify its etiology, describe the outbreak and implement control measures. Methods We described the outbreak using descriptive epidemiology. The study population was defined as students learning in the school where the outbreak occurred. Suspected rubella case was defined as student with generalized rash whereas confirmed case was suspected case tested positive for rubella IgM. Questionnaires, checklists and students record review were used to collect data. We searched for new cases in classes daily and excluded them from classes. The school environment was assessed and the outbreak was described in person and time. Results We identified 58 cases (median age: 4.6 years; IQR: 4–5 years) with six of them rubella IgM positive and 52 epidemiologically linked. The outbreak began on 8 February 2018 having multiple intermittent peaks during its course reaching its highest peak at 2 April, 2018 and ended on 20 April, 2018. Index cases were reported from two classes; however, cases were occurred in 13/15(86.67%) of the classes during the entire outbreak. Fifty five percent (32/58) and 45/58(77.59%) of the cases were females and 3–5 years children, respectively. Overall attack rate was 58/531(4.05%). Attack rate was higher in females 32/252 (12.7%) than in males 26/279 (9.32%), and higher 45/275(16.36%) in 3–5 years than those in 5–8 years 13/256(5.08%) children. Case fatality ratio was zero. All cases were vaccinated against measles but unvaccinated against rubella. Conclusions Attack rate was higher in females than in males and higher in 3–5 years than 5–8 years children. We recommended establishing rubella surveillance system, conducting sero-prevalence of rubella among child bearing age females and establishing CRS surveillance among young infants to provide evidence-based information for RCV introduction. It was also recommended to develop a national rubella surveillance guideline which aid to exclude rubella cases from schools during outbreak.http://link.springer.com/article/10.1186/s12879-019-3873-yDescriptive epidemiologyDisease outbreaksRubellaSchool |
| spellingShingle | Getachew Dinede Abigiya Wondimagegnehu Fikre Enquselassie Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 BMC Infectious Diseases Descriptive epidemiology Disease outbreaks Rubella School |
| title | Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 |
| title_full | Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 |
| title_fullStr | Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 |
| title_full_unstemmed | Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 |
| title_short | Rubella outbreak in the school children, Addis Ababa, Ethiopia: February–April 2018 |
| title_sort | rubella outbreak in the school children addis ababa ethiopia february april 2018 |
| topic | Descriptive epidemiology Disease outbreaks Rubella School |
| url | http://link.springer.com/article/10.1186/s12879-019-3873-y |
| work_keys_str_mv | AT getachewdinede rubellaoutbreakintheschoolchildrenaddisababaethiopiafebruaryapril2018 AT abigiyawondimagegnehu rubellaoutbreakintheschoolchildrenaddisababaethiopiafebruaryapril2018 AT fikreenquselassie rubellaoutbreakintheschoolchildrenaddisababaethiopiafebruaryapril2018 |