Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen
Abstract Full term pregnancy at an early age is the only factor known to consistently protect against breast cancer. Because hormone receptor positive progenitors in the human breast relay endocrine signaling, we here sought to determine whether an experimental mimicry of the third trimester surge o...
Main Authors: | Lone Rønnov-Jessen, Jiyoung Kim, Nadine Goldhammer, Marie Christine Klitgaard, Martynas Smicius, Marc Baker Bechmann, René Villadsen, Ole William Petersen |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-96785-8 |
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