Synthesis of Gallic Acid Analogs as Histamine and Pro-Inflammatory Cytokine Inhibitors for Treatment of Mast Cell-Mediated Allergic Inflammation

Synthesis of Gallic Acid Analogs as Histamine and Pro-Inflammatory Cytokine Inhibitors for Treatment of Mast Cell-Mediated Allergic Inflammation

Gallic acid (3,4,5-trihydroxybenzoic acid), is a natural product found in various foods and herbs that are well known as powerful antioxidants. Our previous report demonstrated that it inhibits mast cell-derived inflammatory allergic reactions by blocking histamine release and pro-inflammatory cytok...

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Bibliographic Details
Main Authors: Xiang Fei, In-Gyu Je, Tae-Yong Shin, Sang-Hyun Kim, Seung-Yong Seo
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
gallic acid
allergic inflammation
histamine
pro-inflammatory cytokine
Online Access:http://www.mdpi.com/1420-3049/22/6/898

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