Pre-arrest doxycycline protects donation after circulatory death kidneys

Pre-arrest doxycycline protects donation after circulatory death kidneys

Abstract Kidney injury during donation after circulatory determination of death (DCDD) includes warm ischemic (WI) injury from around the time of asystole, and cold ischemic (CI) injury during cold preservation. We have previously shown that Matrix Metalloproteinases (MMPs) are involved in CI injury...

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Bibliographic Details
Main Authors: Michael Moser, Sarah Schmid, Katherine Sawicka, Tamalina Banerjee, Erick McNair, Jolanta Sawicka, Iwona Bil-Lula, Grzegorz Sawicki
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79440-6

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