Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis

Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of r...

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Main Authors: Giuseppe Limongelli, Emanuele Monda, Giovanbattista Capozzi, Martina Caiazza, Maria Giovanna Russo
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cardiogenetics
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/cardiogen/article/view/8609
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author Giuseppe Limongelli
Emanuele Monda
Giovanbattista Capozzi
Martina Caiazza
Maria Giovanna Russo
author_facet Giuseppe Limongelli
Emanuele Monda
Giovanbattista Capozzi
Martina Caiazza
Maria Giovanna Russo
author_sort Giuseppe Limongelli
collection DOAJ
description Management of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.
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spelling doaj.art-9d153537de9c494c922c3c8376818baf2022-12-21T19:30:26ZengMDPI AGCardiogenetics2035-82532035-81482020-01-019110.4081/cardiogenetics.2019.8609Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosisGiuseppe Limongelli0Emanuele Monda1Giovanbattista Capozzi2Martina Caiazza3Maria Giovanna Russo4Unit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, Naples, Italy; Institute of Cardiovascular Sciences, University College of LondonUnit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, NaplesUnit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, NaplesUnit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, NaplesUnit of Pediatric Cardiology, Department of Translational Sciences, Luigi Vanvitelli University, AORN Colli, Monaldi Hospital, NaplesManagement of symptoms in patients with inoperable aortic stenosis is often hard in clinical practice. We report a case of a patient with Hutchinson-Gilford progeria syndrome and end-stage aortic stenosis, considered not suitable for surgical or percutaneous approach, to whom the administration of ranolazine resulted in a considerable improvement of angina, refractory to other treatments.https://www.pagepressjournals.org/index.php/cardiogen/article/view/8609Hutchinson-Gilford progeria syndromeaortic stenosisranolazine.
spellingShingle Giuseppe Limongelli
Emanuele Monda
Giovanbattista Capozzi
Martina Caiazza
Maria Giovanna Russo
Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
Cardiogenetics
Hutchinson-Gilford progeria syndrome
aortic stenosis
ranolazine.
title Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
title_full Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
title_fullStr Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
title_full_unstemmed Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
title_short Ranolazine treatment for refractory angina in a patient with Hutchinson-Gilford progeria syndrome and end stage aortic stenosis
title_sort ranolazine treatment for refractory angina in a patient with hutchinson gilford progeria syndrome and end stage aortic stenosis
topic Hutchinson-Gilford progeria syndrome
aortic stenosis
ranolazine.
url https://www.pagepressjournals.org/index.php/cardiogen/article/view/8609
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