Paraganglioma at the cerebellopontine angle: A case report and review of literature
Key Clinical Message Paragangliomas (PGLs) are rare neuroendocrine tumors. Sometimes, these tumors secrete excessive catecholamines, which results in the manifestations of various signs and symptoms, usually with a triad of hypertension, tachycardia, and headache. We report the case of a 42‐year‐old...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-03-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8584 |
| _version_ | 1797244357665882112 |
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| author | Nadeem Akhtar Fatimah Shahid Alishba Shezal Ali Qurat Ul Ain Muhammad Noor Mahal Azam Bishal Dhakal Muhammad Ibrahim Nehal Nadeem |
| author_facet | Nadeem Akhtar Fatimah Shahid Alishba Shezal Ali Qurat Ul Ain Muhammad Noor Mahal Azam Bishal Dhakal Muhammad Ibrahim Nehal Nadeem |
| author_sort | Nadeem Akhtar |
| collection | DOAJ |
| description | Key Clinical Message Paragangliomas (PGLs) are rare neuroendocrine tumors. Sometimes, these tumors secrete excessive catecholamines, which results in the manifestations of various signs and symptoms, usually with a triad of hypertension, tachycardia, and headache. We report the case of a 42‐year‐old woman presenting with uncontrolled hypertension, right facial palsy, vomiting, and disturbed gait. Diagnosis for PGL was confirmed on postoperative histological examination of the excised mass and correlated with preoperative clinical and radiological findings. Tumor excision was done via a suboccipital craniotomy approach. Our case presents the typically severe features of a jugulotympanic PGL, but most importantly, it highlights the necessity of biochemical diagnosing, thorough probing of the causes of hypertension, and a multi‐disciplinary approach in dealing with these tumors. Moreover, the case emphasizes necessitating the use of preoperative embolization in vascular tumors of the head and neck to avoid a hemorrhagic crisis during surgery. Unfortunately, due to a lack of adequate hospital funds, the surgeon had to proceed without preoperative embolization. Despite such a risk, the excision was a success. |
| first_indexed | 2024-04-24T19:09:44Z |
| format | Article |
| id | doaj.art-9d1584c6b4f14dd4bc29e6dd48e50568 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-24T19:09:44Z |
| publishDate | 2024-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-9d1584c6b4f14dd4bc29e6dd48e505682024-03-26T12:36:42ZengWileyClinical Case Reports2050-09042024-03-01123n/an/a10.1002/ccr3.8584Paraganglioma at the cerebellopontine angle: A case report and review of literatureNadeem Akhtar0Fatimah Shahid1Alishba Shezal Ali2Qurat Ul Ain Muhammad3Noor Mahal Azam4Bishal Dhakal5Muhammad Ibrahim6Nehal Nadeem7Department of Neurosurgery Rawalpindi Teaching Hospital Punjab PakistanDepartment of Neurosurgery Rawalpindi Medical University Punjab PakistanDepartment of Neurosurgery Rawalpindi Medical University Punjab PakistanDepartment of Neurosurgery Rawalpindi Medical University Punjab PakistanDepartment of Neurosurgery Rawalpindi Medical University Punjab PakistanDepartment of Neurology Nepalese Army Institute of Health Sciences Kathmandu NepalDepartment of Neurosurgery Rawalpindi Medical University Punjab PakistanDepartment of Internal Medicine Shifa College of Medicine Islamabad PakistanKey Clinical Message Paragangliomas (PGLs) are rare neuroendocrine tumors. Sometimes, these tumors secrete excessive catecholamines, which results in the manifestations of various signs and symptoms, usually with a triad of hypertension, tachycardia, and headache. We report the case of a 42‐year‐old woman presenting with uncontrolled hypertension, right facial palsy, vomiting, and disturbed gait. Diagnosis for PGL was confirmed on postoperative histological examination of the excised mass and correlated with preoperative clinical and radiological findings. Tumor excision was done via a suboccipital craniotomy approach. Our case presents the typically severe features of a jugulotympanic PGL, but most importantly, it highlights the necessity of biochemical diagnosing, thorough probing of the causes of hypertension, and a multi‐disciplinary approach in dealing with these tumors. Moreover, the case emphasizes necessitating the use of preoperative embolization in vascular tumors of the head and neck to avoid a hemorrhagic crisis during surgery. Unfortunately, due to a lack of adequate hospital funds, the surgeon had to proceed without preoperative embolization. Despite such a risk, the excision was a success.https://doi.org/10.1002/ccr3.8584catecholamine secreting tumorcerebellopontine angleextra‐adrenal paragangliomahead and neck neoplasmshypertensionhypoxia‐inducible factor (HIF)‐1α |
| spellingShingle | Nadeem Akhtar Fatimah Shahid Alishba Shezal Ali Qurat Ul Ain Muhammad Noor Mahal Azam Bishal Dhakal Muhammad Ibrahim Nehal Nadeem Paraganglioma at the cerebellopontine angle: A case report and review of literature Clinical Case Reports catecholamine secreting tumor cerebellopontine angle extra‐adrenal paraganglioma head and neck neoplasms hypertension hypoxia‐inducible factor (HIF)‐1α |
| title | Paraganglioma at the cerebellopontine angle: A case report and review of literature |
| title_full | Paraganglioma at the cerebellopontine angle: A case report and review of literature |
| title_fullStr | Paraganglioma at the cerebellopontine angle: A case report and review of literature |
| title_full_unstemmed | Paraganglioma at the cerebellopontine angle: A case report and review of literature |
| title_short | Paraganglioma at the cerebellopontine angle: A case report and review of literature |
| title_sort | paraganglioma at the cerebellopontine angle a case report and review of literature |
| topic | catecholamine secreting tumor cerebellopontine angle extra‐adrenal paraganglioma head and neck neoplasms hypertension hypoxia‐inducible factor (HIF)‐1α |
| url | https://doi.org/10.1002/ccr3.8584 |
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