Prevalence and predictors of post-COVID-19 pulmonary fibrosis
Background Several studies are ongoing to obtain more information about post-COVID-19 (corona virus disease-19) pulmonary fibrosis. Old-aged patients are more likely to evolve lung fibrosis in COVID-19. Another risk factor is the degree of disease severity, including comorbidities, such as hypertens...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Egyptian Journal of Chest Disease and Tuberculosis |
| Subjects: | |
| Online Access: | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2022;volume=71;issue=4;spage=481;epage=484;aulast=Alkhayat |
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| author | Khaled Fawzy Alkhayat Doaa Gadallah Mohamed Hamed Hasan Abdelhady Ragab Abdel-Gawad Eman Roshdy Mohamed Asmaa Ramadan Bakir |
| author_facet | Khaled Fawzy Alkhayat Doaa Gadallah Mohamed Hamed Hasan Abdelhady Ragab Abdel-Gawad Eman Roshdy Mohamed Asmaa Ramadan Bakir |
| author_sort | Khaled Fawzy Alkhayat |
| collection | DOAJ |
| description | Background Several studies are ongoing to obtain more information about post-COVID-19 (corona virus disease-19) pulmonary fibrosis. Old-aged patients are more likely to evolve lung fibrosis in COVID-19. Another risk factor is the degree of disease severity, including comorbidities, such as hypertension, diabetes, as well as lab findings, for example, lymphopenia and leukocytosis. Aims of work To assess the prevalence of post-COVID-19 pulmonary fibrosis and reveal some of its predictors. Results The study included 50 patients in the outpatient clinics of Chest and EL-Helal Hospitals with a mean age of 49.6 ± 17.7 years. It included 32 (64%) males and 18 (36%) females. Pulmonary fibrosis was detected in 34 (68%) patients. Pulmonary fibrosis was bilateral in 24 patients and unilateral in 10 patients. Leucopenia, elevated serum ferritin, elevated D-dimer, and elevated C-reactive protein (CRP) were associated with pulmonary fibrosis (P value <0.001). Conclusion Pulmonary fibrosis is recognized as a complication between survivors. Immune response due to lung injury by viral infection, and trials to repair are keys to the procedure of fibro genesis. Predictors of lung fibrosis involve increased lab parameters such as serum ferritin, C-reactive protein, and D-dimer. |
| first_indexed | 2024-04-12T02:07:13Z |
| format | Article |
| id | doaj.art-9d15a5bc14054e0292a3938cbe1f47d4 |
| institution | Directory Open Access Journal |
| issn | 0422-7638 2090-9950 |
| language | English |
| last_indexed | 2024-04-12T02:07:13Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Egyptian Journal of Chest Disease and Tuberculosis |
| spelling | doaj.art-9d15a5bc14054e0292a3938cbe1f47d42022-12-22T03:52:30ZengWolters Kluwer Medknow PublicationsEgyptian Journal of Chest Disease and Tuberculosis0422-76382090-99502022-01-0171448148410.4103/ecdt.ecdt_76_21Prevalence and predictors of post-COVID-19 pulmonary fibrosisKhaled Fawzy AlkhayatDoaa GadallahMohamed Hamed HasanAbdelhady Ragab Abdel-GawadEman Roshdy MohamedAsmaa Ramadan BakirBackground Several studies are ongoing to obtain more information about post-COVID-19 (corona virus disease-19) pulmonary fibrosis. Old-aged patients are more likely to evolve lung fibrosis in COVID-19. Another risk factor is the degree of disease severity, including comorbidities, such as hypertension, diabetes, as well as lab findings, for example, lymphopenia and leukocytosis. Aims of work To assess the prevalence of post-COVID-19 pulmonary fibrosis and reveal some of its predictors. Results The study included 50 patients in the outpatient clinics of Chest and EL-Helal Hospitals with a mean age of 49.6 ± 17.7 years. It included 32 (64%) males and 18 (36%) females. Pulmonary fibrosis was detected in 34 (68%) patients. Pulmonary fibrosis was bilateral in 24 patients and unilateral in 10 patients. Leucopenia, elevated serum ferritin, elevated D-dimer, and elevated C-reactive protein (CRP) were associated with pulmonary fibrosis (P value <0.001). Conclusion Pulmonary fibrosis is recognized as a complication between survivors. Immune response due to lung injury by viral infection, and trials to repair are keys to the procedure of fibro genesis. Predictors of lung fibrosis involve increased lab parameters such as serum ferritin, C-reactive protein, and D-dimer.http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2022;volume=71;issue=4;spage=481;epage=484;aulast=Alkhayatcovid-19d-dimerpulmonary fibrosis |
| spellingShingle | Khaled Fawzy Alkhayat Doaa Gadallah Mohamed Hamed Hasan Abdelhady Ragab Abdel-Gawad Eman Roshdy Mohamed Asmaa Ramadan Bakir Prevalence and predictors of post-COVID-19 pulmonary fibrosis Egyptian Journal of Chest Disease and Tuberculosis covid-19 d-dimer pulmonary fibrosis |
| title | Prevalence and predictors of post-COVID-19 pulmonary fibrosis |
| title_full | Prevalence and predictors of post-COVID-19 pulmonary fibrosis |
| title_fullStr | Prevalence and predictors of post-COVID-19 pulmonary fibrosis |
| title_full_unstemmed | Prevalence and predictors of post-COVID-19 pulmonary fibrosis |
| title_short | Prevalence and predictors of post-COVID-19 pulmonary fibrosis |
| title_sort | prevalence and predictors of post covid 19 pulmonary fibrosis |
| topic | covid-19 d-dimer pulmonary fibrosis |
| url | http://www.ejcdt.eg.net/article.asp?issn=0422-7638;year=2022;volume=71;issue=4;spage=481;epage=484;aulast=Alkhayat |
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