Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands
Quantitative coprological analyses of children were performed in Alexandria and Behera governorates, Egypt, to ascertain whether individual intensities in the Nile Delta lowlands reach high levels as those known in hyperendemic highland areas of Latin America. Analyses focused on subjects presenting...
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MDPI AG
2021-09-01
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| author | M. Victoria Periago M. Adela Valero Patricio Artigas Verónica H. Agramunt M. Dolores Bargues Filippo Curtale Santiago Mas-Coma |
| author_facet | M. Victoria Periago M. Adela Valero Patricio Artigas Verónica H. Agramunt M. Dolores Bargues Filippo Curtale Santiago Mas-Coma |
| author_sort | M. Victoria Periago |
| collection | DOAJ |
| description | Quantitative coprological analyses of children were performed in Alexandria and Behera governorates, Egypt, to ascertain whether individual intensities in the Nile Delta lowlands reach high levels as those known in hyperendemic highland areas of Latin America. Analyses focused on subjects presenting intensities higher than 400 eggs per gram of faeces (epg), the high burden cut-off according to WHO classification. A total of 96 children were found to shed between 408 and 2304 epg, with arithmetic and geometric means of 699.5 and 629.07 epg, respectively. Intensities found are the highest hitherto recorded in Egypt, and also in the whole Old World. A total of 38 (39.6%) were males and 58 (60.4%) were females, with high intensities according to gender following a negative binomial distribution. The high burden distribution shows a peak in the 7–10 year-old children group, more precocious in females than males. Results showed high burdens in winter to be remarkably higher than those known in summer. The fascioliasis scenario in Egyptian lowlands shows similarities to highlands of Bolivia and Peru. Diagnostic methods, pathogenicity and morbidity in high burdens should be considered. The need for an appropriate quantitative assessment of heavy infected children to avoid post-treatment colic episodes is highlighted. |
| first_indexed | 2024-03-10T07:19:28Z |
| format | Article |
| id | doaj.art-9d188ea839ac4cf496d4697ca1311eb3 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T07:19:28Z |
| publishDate | 2021-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-9d188ea839ac4cf496d4697ca1311eb32023-11-22T14:43:24ZengMDPI AGPathogens2076-08172021-09-01109121010.3390/pathogens10091210Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in LowlandsM. Victoria Periago0M. Adela Valero1Patricio Artigas2Verónica H. Agramunt3M. Dolores Bargues4Filippo Curtale5Santiago Mas-Coma6Departamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainU.O.C. Rapporti internazionali, con le Regioni e Gestione del Ciclo di Progetto, Istituto Nazionale per la Promozione della Salute delle Popolazioni Migranti e il Contrasto delle Malattie della Povertà, 00153 Roma, ItalyDepartamento de Parasitología, Facultad de Farmacia, Universidad de Valencia, Av. Vicent Andres Estelles s/n, 46100 Valencia, SpainQuantitative coprological analyses of children were performed in Alexandria and Behera governorates, Egypt, to ascertain whether individual intensities in the Nile Delta lowlands reach high levels as those known in hyperendemic highland areas of Latin America. Analyses focused on subjects presenting intensities higher than 400 eggs per gram of faeces (epg), the high burden cut-off according to WHO classification. A total of 96 children were found to shed between 408 and 2304 epg, with arithmetic and geometric means of 699.5 and 629.07 epg, respectively. Intensities found are the highest hitherto recorded in Egypt, and also in the whole Old World. A total of 38 (39.6%) were males and 58 (60.4%) were females, with high intensities according to gender following a negative binomial distribution. The high burden distribution shows a peak in the 7–10 year-old children group, more precocious in females than males. Results showed high burdens in winter to be remarkably higher than those known in summer. The fascioliasis scenario in Egyptian lowlands shows similarities to highlands of Bolivia and Peru. Diagnostic methods, pathogenicity and morbidity in high burdens should be considered. The need for an appropriate quantitative assessment of heavy infected children to avoid post-treatment colic episodes is highlighted.https://www.mdpi.com/2076-0817/10/9/1210human fascioliasischildrencoprologyhigh intensitiesgender and agegeographical distribution |
| spellingShingle | M. Victoria Periago M. Adela Valero Patricio Artigas Verónica H. Agramunt M. Dolores Bargues Filippo Curtale Santiago Mas-Coma Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands Pathogens human fascioliasis children coprology high intensities gender and age geographical distribution |
| title | Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands |
| title_full | Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands |
| title_fullStr | Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands |
| title_full_unstemmed | Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands |
| title_short | Very High Fascioliasis Intensities in Schoolchildren from Nile Delta Governorates, Egypt: The Old World Highest Burdens Found in Lowlands |
| title_sort | very high fascioliasis intensities in schoolchildren from nile delta governorates egypt the old world highest burdens found in lowlands |
| topic | human fascioliasis children coprology high intensities gender and age geographical distribution |
| url | https://www.mdpi.com/2076-0817/10/9/1210 |
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