Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect

Spinal disorders cover a broad spectrum of pathologies and are among the most prevalent medical conditions. The management of these health issues was noted to be increasingly based on surgical interventions. Spinal fixation devices are often employed to improve surgery outcomes, increasing spinal st...

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Main Authors: Bogdan Costăchescu, Adelina-Gabriela Niculescu, Alexandru Mihai Grumezescu, Daniel Mihai Teleanu
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/16/16/5582
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author Bogdan Costăchescu
Adelina-Gabriela Niculescu
Alexandru Mihai Grumezescu
Daniel Mihai Teleanu
author_facet Bogdan Costăchescu
Adelina-Gabriela Niculescu
Alexandru Mihai Grumezescu
Daniel Mihai Teleanu
author_sort Bogdan Costăchescu
collection DOAJ
description Spinal disorders cover a broad spectrum of pathologies and are among the most prevalent medical conditions. The management of these health issues was noted to be increasingly based on surgical interventions. Spinal fixation devices are often employed to improve surgery outcomes, increasing spinal stability, restoring structural integrity, and ensuring functionality. However, most of the currently used fixation tools are fabricated from materials with very different mechanical properties to native bone that are prone to pull-out effects or fail over time, requiring revision procedures. Solutions to these problems presently exploited in practice include the optimal selection of screw shape and size, modification of insertion trajectory, and utilization of bone cement to reinforce fixation constructs. Nevertheless, none of these methods are without risks and limitations. An alternative option to increasing biomechanical resistance to the pull-out effect is to tackle bone regenerative capacity and focus on screw osteointegration properties. Osteointegration was reportedly enhanced through various optimization strategies, including use of novel materials, surface modification techniques (e.g., application of coatings and topological optimization), and utilization of composites that allow synergistic effects between constituents. In this context, this paper takes a comprehensive path, starting with a brief presentation of spinal fixation devices, moving further to observations on how the pull-out strength can be enhanced with existing methods, and further focusing on techniques for implant osteointegration improvement.
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spelling doaj.art-9d1e79a0b92f4e029eb674b077c476912023-11-19T01:59:42ZengMDPI AGMaterials1996-19442023-08-011616558210.3390/ma16165582Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out EffectBogdan Costăchescu0Adelina-Gabriela Niculescu1Alexandru Mihai Grumezescu2Daniel Mihai Teleanu3“Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaResearch Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, RomaniaResearch Institute of the University of Bucharest—ICUB, University of Bucharest, 050657 Bucharest, Romania“Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, RomaniaSpinal disorders cover a broad spectrum of pathologies and are among the most prevalent medical conditions. The management of these health issues was noted to be increasingly based on surgical interventions. Spinal fixation devices are often employed to improve surgery outcomes, increasing spinal stability, restoring structural integrity, and ensuring functionality. However, most of the currently used fixation tools are fabricated from materials with very different mechanical properties to native bone that are prone to pull-out effects or fail over time, requiring revision procedures. Solutions to these problems presently exploited in practice include the optimal selection of screw shape and size, modification of insertion trajectory, and utilization of bone cement to reinforce fixation constructs. Nevertheless, none of these methods are without risks and limitations. An alternative option to increasing biomechanical resistance to the pull-out effect is to tackle bone regenerative capacity and focus on screw osteointegration properties. Osteointegration was reportedly enhanced through various optimization strategies, including use of novel materials, surface modification techniques (e.g., application of coatings and topological optimization), and utilization of composites that allow synergistic effects between constituents. In this context, this paper takes a comprehensive path, starting with a brief presentation of spinal fixation devices, moving further to observations on how the pull-out strength can be enhanced with existing methods, and further focusing on techniques for implant osteointegration improvement.https://www.mdpi.com/1996-1944/16/16/5582bone fixationspinal fixation devicesspinal screwspull-out effectreinforcement strategiesosteointegration
spellingShingle Bogdan Costăchescu
Adelina-Gabriela Niculescu
Alexandru Mihai Grumezescu
Daniel Mihai Teleanu
Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
Materials
bone fixation
spinal fixation devices
spinal screws
pull-out effect
reinforcement strategies
osteointegration
title Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
title_full Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
title_fullStr Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
title_full_unstemmed Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
title_short Screw Osteointegration—Increasing Biomechanical Resistance to Pull-Out Effect
title_sort screw osteointegration increasing biomechanical resistance to pull out effect
topic bone fixation
spinal fixation devices
spinal screws
pull-out effect
reinforcement strategies
osteointegration
url https://www.mdpi.com/1996-1944/16/16/5582
work_keys_str_mv AT bogdancostachescu screwosteointegrationincreasingbiomechanicalresistancetopullouteffect
AT adelinagabrielaniculescu screwosteointegrationincreasingbiomechanicalresistancetopullouteffect
AT alexandrumihaigrumezescu screwosteointegrationincreasingbiomechanicalresistancetopullouteffect
AT danielmihaiteleanu screwosteointegrationincreasingbiomechanicalresistancetopullouteffect