High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume
We present the fabrication and evaluation of microdebubblers that are able to remove large bubbles while keeping a very low dead volume. The devices use a polytetrafluoroethylene membrane that is permeable to air in order to filter air bubbles out of an aqueous sample. The dead volume of the devices...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-03-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-666X/3/2/218/ |
| _version_ | 1818842288768417792 |
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| author | Philippe Renaud Harald van Lintel Guillaume Mernier |
| author_facet | Philippe Renaud Harald van Lintel Guillaume Mernier |
| author_sort | Philippe Renaud |
| collection | DOAJ |
| description | We present the fabrication and evaluation of microdebubblers that are able to remove large bubbles while keeping a very low dead volume. The devices use a polytetrafluoroethylene membrane that is permeable to air in order to filter air bubbles out of an aqueous sample. The dead volume of the devices is less than one microliter, but bubbles as large as 60 microliters can be removed. This simple solution can be very useful for microfluidic devices for chemical or biological analysis that suffer from channel clogging due to the presence of bubbles in their sample. One embodiment is particularly suited for buffer solutions with living cells. |
| first_indexed | 2024-12-19T04:39:36Z |
| format | Article |
| id | doaj.art-9d220b5d532b47518982018c512a239e |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-12-19T04:39:36Z |
| publishDate | 2012-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-9d220b5d532b47518982018c512a239e2022-12-21T20:35:39ZengMDPI AGMicromachines2072-666X2012-03-013221822410.3390/mi3020218High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead VolumePhilippe RenaudHarald van LintelGuillaume MernierWe present the fabrication and evaluation of microdebubblers that are able to remove large bubbles while keeping a very low dead volume. The devices use a polytetrafluoroethylene membrane that is permeable to air in order to filter air bubbles out of an aqueous sample. The dead volume of the devices is less than one microliter, but bubbles as large as 60 microliters can be removed. This simple solution can be very useful for microfluidic devices for chemical or biological analysis that suffer from channel clogging due to the presence of bubbles in their sample. One embodiment is particularly suited for buffer solutions with living cells.http://www.mdpi.com/2072-666X/3/2/218/microfluidicsdebubblerair bubblesyeast cells |
| spellingShingle | Philippe Renaud Harald van Lintel Guillaume Mernier High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume Micromachines microfluidics debubbler air bubbles yeast cells |
| title | High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume |
| title_full | High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume |
| title_fullStr | High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume |
| title_full_unstemmed | High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume |
| title_short | High-Throughput Micro-Debubblers for Bubble Removal with Sub-Microliter Dead Volume |
| title_sort | high throughput micro debubblers for bubble removal with sub microliter dead volume |
| topic | microfluidics debubbler air bubbles yeast cells |
| url | http://www.mdpi.com/2072-666X/3/2/218/ |
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