Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target
Studying the specific roles of macrophage subsets has been hampered by a lack of subset-specific probes. Here the authors report an M1 selective fluorescent probe named CDr17, and demonstrate the suitability of this probe for tracking M1 macrophages in vivo.
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-33526-z |
| _version_ | 1811238640971415552 |
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| author | Heewon Cho Haw-Young Kwon Amit Sharma Sun Hyeok Lee Xiao Liu Naoki Miyamoto Jong-Jin Kim Sin-Hyeog Im Nam-Young Kang Young-Tae Chang |
| author_facet | Heewon Cho Haw-Young Kwon Amit Sharma Sun Hyeok Lee Xiao Liu Naoki Miyamoto Jong-Jin Kim Sin-Hyeog Im Nam-Young Kang Young-Tae Chang |
| author_sort | Heewon Cho |
| collection | DOAJ |
| description | Studying the specific roles of macrophage subsets has been hampered by a lack of subset-specific probes. Here the authors report an M1 selective fluorescent probe named CDr17, and demonstrate the suitability of this probe for tracking M1 macrophages in vivo. |
| first_indexed | 2024-04-12T12:46:11Z |
| format | Article |
| id | doaj.art-9d22797d096d44b6b006ce06f63551e8 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T12:46:11Z |
| publishDate | 2022-10-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-9d22797d096d44b6b006ce06f63551e82022-12-22T03:32:36ZengNature PortfolioNature Communications2041-17232022-10-011311810.1038/s41467-022-33526-zVisualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating targetHeewon Cho0Haw-Young Kwon1Amit Sharma2Sun Hyeok Lee3Xiao Liu4Naoki Miyamoto5Jong-Jin Kim6Sin-Hyeog Im7Nam-Young Kang8Young-Tae Chang9School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)Center for Self-assembly and Complexity, Institute for Basic Science (IBS)Department of Life Sciences, Pohang University of Science and Technology (POSTECH)School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)Department of Chemistry, Pohang University of Science and Technology (POSTECH)Center for Self-assembly and Complexity, Institute for Basic Science (IBS)Department of Biology, Sunchon National UniversityDepartment of Life Sciences, Pohang University of Science and Technology (POSTECH)Department of Convergence IT Engineering, Pohang University of Science and Technology (POSTECH)School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)Studying the specific roles of macrophage subsets has been hampered by a lack of subset-specific probes. Here the authors report an M1 selective fluorescent probe named CDr17, and demonstrate the suitability of this probe for tracking M1 macrophages in vivo.https://doi.org/10.1038/s41467-022-33526-z |
| spellingShingle | Heewon Cho Haw-Young Kwon Amit Sharma Sun Hyeok Lee Xiao Liu Naoki Miyamoto Jong-Jin Kim Sin-Hyeog Im Nam-Young Kang Young-Tae Chang Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target Nature Communications |
| title | Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target |
| title_full | Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target |
| title_fullStr | Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target |
| title_full_unstemmed | Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target |
| title_short | Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target |
| title_sort | visualizing inflammation with an m1 macrophage selective probe via glut1 as the gating target |
| url | https://doi.org/10.1038/s41467-022-33526-z |
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