Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications
Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradab...
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Format: | Article |
Language: | English |
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MDPI AG
2023-03-01
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Series: | Gels |
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Online Access: | https://www.mdpi.com/2310-2861/9/4/277 |
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author | Siriporn Taokaew Worasak Kaewkong Worawut Kriangkrai |
author_facet | Siriporn Taokaew Worasak Kaewkong Worawut Kriangkrai |
author_sort | Siriporn Taokaew |
collection | DOAJ |
description | Chitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradability, and non-immunogenicity. In this review, the advanced functions of the chitosan-based hydrogels are summarized, with emphasis on fabrications and resultant properties reported in literature from the recent decade. The recent progress in the applications of drug delivery, tissue engineering, disease treatments, and biosensors are reviewed. Current challenges and future development direction of the chitosan-based hydrogels for pharmaceutical and biomedical applications are prospected. |
first_indexed | 2024-03-11T05:00:18Z |
format | Article |
id | doaj.art-9d22d3940c834ad08f7cd7ced0c4cc0a |
institution | Directory Open Access Journal |
issn | 2310-2861 |
language | English |
last_indexed | 2024-03-11T05:00:18Z |
publishDate | 2023-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Gels |
spelling | doaj.art-9d22d3940c834ad08f7cd7ced0c4cc0a2023-11-17T19:21:10ZengMDPI AGGels2310-28612023-03-019427710.3390/gels9040277Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical ApplicationsSiriporn Taokaew0Worasak Kaewkong1Worawut Kriangkrai2Department of Materials Science and Bioengineering, School of Engineering, Nagaoka University of Technology, Nagaoka 940-2188, JapanDepartment of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok 65000, ThailandDepartment of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, ThailandChitosan is a promising naturally derived polysaccharide to be used in hydrogel forms for pharmaceutical and biomedical applications. The multifunctional chitosan-based hydrogels have attractive properties such as the ability to encapsulate, carry, and release the drug, biocompatibility, biodegradability, and non-immunogenicity. In this review, the advanced functions of the chitosan-based hydrogels are summarized, with emphasis on fabrications and resultant properties reported in literature from the recent decade. The recent progress in the applications of drug delivery, tissue engineering, disease treatments, and biosensors are reviewed. Current challenges and future development direction of the chitosan-based hydrogels for pharmaceutical and biomedical applications are prospected.https://www.mdpi.com/2310-2861/9/4/277chitosanmultifunctional hydrogelsfabricationbiomedical applicationscontrolled drug delivery |
spellingShingle | Siriporn Taokaew Worasak Kaewkong Worawut Kriangkrai Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications Gels chitosan multifunctional hydrogels fabrication biomedical applications controlled drug delivery |
title | Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications |
title_full | Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications |
title_fullStr | Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications |
title_full_unstemmed | Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications |
title_short | Recent Development of Functional Chitosan-Based Hydrogels for Pharmaceutical and Biomedical Applications |
title_sort | recent development of functional chitosan based hydrogels for pharmaceutical and biomedical applications |
topic | chitosan multifunctional hydrogels fabrication biomedical applications controlled drug delivery |
url | https://www.mdpi.com/2310-2861/9/4/277 |
work_keys_str_mv | AT siriporntaokaew recentdevelopmentoffunctionalchitosanbasedhydrogelsforpharmaceuticalandbiomedicalapplications AT worasakkaewkong recentdevelopmentoffunctionalchitosanbasedhydrogelsforpharmaceuticalandbiomedicalapplications AT worawutkriangkrai recentdevelopmentoffunctionalchitosanbasedhydrogelsforpharmaceuticalandbiomedicalapplications |