Regulation and Functions of ROP GTPases in Plant–Microbe Interactions
Rho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell surface immune receptor kinases and intracellular...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
|
| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/9/9/2016 |
| _version_ | 1797554853894946816 |
|---|---|
| author | Stefan Engelhardt Adriana Trutzenberg Ralph Hückelhoven |
| author_facet | Stefan Engelhardt Adriana Trutzenberg Ralph Hückelhoven |
| author_sort | Stefan Engelhardt |
| collection | DOAJ |
| description | Rho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell surface immune receptor kinases and intracellular nucleotide-binding leucine-rich repeat receptors, which activate major branches of plant immune signaling. Additionally, invasive fungal pathogens may co-opt the function of ROPs for manipulation of the cytoskeleton, cell invasion and host cell developmental reprogramming, which promote pathogenic colonization. Strikingly, mammalian bacterial pathogens also initiate both effector-triggered susceptibility for cell invasion and effector-triggered immunity via Rho GTPases. In this review, we summarize central concepts of Rho signaling in disease and immunity of plants and briefly compare them to important findings in the mammalian research field. We focus on Rho activation, downstream signaling and cellular reorganization under control of Rho proteins involved in disease progression and pathogen resistance. |
| first_indexed | 2024-03-10T16:38:01Z |
| format | Article |
| id | doaj.art-9d235b929617478bafb6720b50a8f94f |
| institution | Directory Open Access Journal |
| issn | 2073-4409 |
| language | English |
| last_indexed | 2024-03-10T16:38:01Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cells |
| spelling | doaj.art-9d235b929617478bafb6720b50a8f94f2023-11-20T12:16:12ZengMDPI AGCells2073-44092020-09-0199201610.3390/cells9092016Regulation and Functions of ROP GTPases in Plant–Microbe InteractionsStefan Engelhardt0Adriana Trutzenberg1Ralph Hückelhoven2Phytopathology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Straße 2, 85354 Freising, GermanyPhytopathology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Straße 2, 85354 Freising, GermanyPhytopathology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Straße 2, 85354 Freising, GermanyRho proteins of plants (ROPs) form a specific clade of Rho GTPases, which are involved in either plant immunity or susceptibility to diseases. They are intensively studied in grass host plants, in which ROPs are signaling hubs downstream of both cell surface immune receptor kinases and intracellular nucleotide-binding leucine-rich repeat receptors, which activate major branches of plant immune signaling. Additionally, invasive fungal pathogens may co-opt the function of ROPs for manipulation of the cytoskeleton, cell invasion and host cell developmental reprogramming, which promote pathogenic colonization. Strikingly, mammalian bacterial pathogens also initiate both effector-triggered susceptibility for cell invasion and effector-triggered immunity via Rho GTPases. In this review, we summarize central concepts of Rho signaling in disease and immunity of plants and briefly compare them to important findings in the mammalian research field. We focus on Rho activation, downstream signaling and cellular reorganization under control of Rho proteins involved in disease progression and pathogen resistance.https://www.mdpi.com/2073-4409/9/9/2016Arabidopsisbarleyplant immunityROP GTPasericedisease susceptibility |
| spellingShingle | Stefan Engelhardt Adriana Trutzenberg Ralph Hückelhoven Regulation and Functions of ROP GTPases in Plant–Microbe Interactions Cells Arabidopsis barley plant immunity ROP GTPase rice disease susceptibility |
| title | Regulation and Functions of ROP GTPases in Plant–Microbe Interactions |
| title_full | Regulation and Functions of ROP GTPases in Plant–Microbe Interactions |
| title_fullStr | Regulation and Functions of ROP GTPases in Plant–Microbe Interactions |
| title_full_unstemmed | Regulation and Functions of ROP GTPases in Plant–Microbe Interactions |
| title_short | Regulation and Functions of ROP GTPases in Plant–Microbe Interactions |
| title_sort | regulation and functions of rop gtpases in plant microbe interactions |
| topic | Arabidopsis barley plant immunity ROP GTPase rice disease susceptibility |
| url | https://www.mdpi.com/2073-4409/9/9/2016 |
| work_keys_str_mv | AT stefanengelhardt regulationandfunctionsofropgtpasesinplantmicrobeinteractions AT adrianatrutzenberg regulationandfunctionsofropgtpasesinplantmicrobeinteractions AT ralphhuckelhoven regulationandfunctionsofropgtpasesinplantmicrobeinteractions |