Identification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers

Identification of Transporter Polymorphisms Influencing Metformin Pharmacokinetics in Healthy Volunteers

For patients with type 2 diabetes, metformin is the most often recommended drug. However, there are substantial individual differences in the pharmacological response to metformin. To investigate the effect of transporter polymorphisms on metformin pharmacokinetics in an environment free of confound...

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Bibliographic Details
Main Authors: Miriam Saiz-Rodríguez, Dolores Ochoa, Pablo Zubiaur, Marcos Navares-Gómez, Manuel Román, Paola Camargo-Mamani, Sergio Luquero-Bueno, Gonzalo Villapalos-García, Raquel Alcaraz, Gina Mejía-Abril, Estefanía Santos-Mazo, Francisco Abad-Santos
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Personalized Medicine
Subjects:
metformin
pharmacogenetics
transporters
SLC
ABC
sex
Online Access:https://www.mdpi.com/2075-4426/13/3/489

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