Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury

The purpose of the study was to define a role of thrombocytic-vascular hemostasis in the development of pulmonary complications in severe brain injury. Forty-six patients with severe brain injury were studied over time. Thrombocytic-vascular hemostasis was evaluated by the venous and arterial blood...

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Main Authors: Yu. A. Churlyaev, L. Yu. Redkokasha
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2006-08-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/1117
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author Yu. A. Churlyaev
L. Yu. Redkokasha
author_facet Yu. A. Churlyaev
L. Yu. Redkokasha
author_sort Yu. A. Churlyaev
collection DOAJ
description The purpose of the study was to define a role of thrombocytic-vascular hemostasis in the development of pulmonary complications in severe brain injury. Forty-six patients with severe brain injury were studied over time. Thrombocytic-vascular hemostasis was evaluated by the venous and arterial blood count of platelets and their aggregation induced by epinephrine, ristomycin, and adenosine diphosphate. The studies indicated that there was a reduction in the count of platelets in both venous and arterial blood. At the same time, with a greater degree of lung lesion, there were a reduction and cessation of the venous-arterial difference by the count of platelets, as well as an increase in the aggregatory properties of platelets, which was most profound in arterial blood. The progressive reduction in the levels of platelets in both venous and arterial blood reflected the involvement of platelets in aggregates, on the one hand, and a response to pulmonary vascular endothelial damage and the severity of lung lesion, on the other.
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spelling doaj.art-9d27aad9d3d84149a47caae42fc7b2e12023-03-13T09:32:46ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102006-08-0124222510.15360/1813-9779-2006-4-22-251117Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain InjuryYu. A. Churlyaev0L. Yu. Redkokasha1Филиал ГУ НИИ общей реаниматологии РАМН, Новокузнецк, РоссияФилиал ГУ НИИ общей реаниматологии РАМН, Новокузнецк, РоссияThe purpose of the study was to define a role of thrombocytic-vascular hemostasis in the development of pulmonary complications in severe brain injury. Forty-six patients with severe brain injury were studied over time. Thrombocytic-vascular hemostasis was evaluated by the venous and arterial blood count of platelets and their aggregation induced by epinephrine, ristomycin, and adenosine diphosphate. The studies indicated that there was a reduction in the count of platelets in both venous and arterial blood. At the same time, with a greater degree of lung lesion, there were a reduction and cessation of the venous-arterial difference by the count of platelets, as well as an increase in the aggregatory properties of platelets, which was most profound in arterial blood. The progressive reduction in the levels of platelets in both venous and arterial blood reflected the involvement of platelets in aggregates, on the one hand, and a response to pulmonary vascular endothelial damage and the severity of lung lesion, on the other.https://www.reanimatology.com/rmt/article/view/1117тромбоцитарно-сосудистый гемостазтромбоцитытяжелая черепно-мозговая травмалегочные осложненияордс
spellingShingle Yu. A. Churlyaev
L. Yu. Redkokasha
Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
Общая реаниматология
тромбоцитарно-сосудистый гемостаз
тромбоциты
тяжелая черепно-мозговая травма
легочные осложнения
ордс
title Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
title_full Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
title_fullStr Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
title_full_unstemmed Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
title_short Role of Thrombocytic-Vascular Hemostasis in the Development of Pulmonary Complications in Severe Brain Injury
title_sort role of thrombocytic vascular hemostasis in the development of pulmonary complications in severe brain injury
topic тромбоцитарно-сосудистый гемостаз
тромбоциты
тяжелая черепно-мозговая травма
легочные осложнения
ордс
url https://www.reanimatology.com/rmt/article/view/1117
work_keys_str_mv AT yuachurlyaev roleofthrombocyticvascularhemostasisinthedevelopmentofpulmonarycomplicationsinseverebraininjury
AT lyuredkokasha roleofthrombocyticvascularhemostasisinthedevelopmentofpulmonarycomplicationsinseverebraininjury