IL‐2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

IL‐2 modulates Th2 cell responses to glucocorticosteroid: A cause of persistent type 2 inflammation?

Abstract Background Glucocorticosteroids (GCs) are the main treatment for asthma as they reduce type 2 cytokine expression and induce apoptosis. Asthma severity is associated with type 2 inflammation, circulating Th2 cells and higher GC requirements. Objective The aim of this study was to assess whe...

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Bibliographic Details
Main Authors: Tharsan Kanagalingam, Lauren Solomon, Meerah Vijeyakumaran, Nami Shrestha Palikhe, Harissios Vliagoftis, Lisa Cameron
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Immunity, Inflammation and Disease
Subjects:
apoptosis
asthma
IL‐13
IL‐2
steroid
Th2 cells
Online Access:https://doi.org/10.1002/iid3.249

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