Peptide-Based Hydrogels: Template Materials for Tissue Engineering
Tissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition. As well known, peptide hydrogels have attracted increasing attention in recent years than...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Journal of Functional Biomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4983/14/4/233 |
| _version_ | 1797604889497436160 |
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| author | Roya Binaymotlagh Laura Chronopoulou Cleofe Palocci |
| author_facet | Roya Binaymotlagh Laura Chronopoulou Cleofe Palocci |
| author_sort | Roya Binaymotlagh |
| collection | DOAJ |
| description | Tissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition. As well known, peptide hydrogels have attracted increasing attention in recent years thanks to significant properties such as biocompatibility, biodegradability, good mechanical stability, and tissue-like elasticity. Such properties make them excellent candidates for 3D scaffold materials. In this review, the first aim is to describe the main features of a peptide hydrogel in order to be considered as a 3D scaffold, focusing in particular on mechanical properties, as well as on biodegradability and bioactivity. Then, some recent applications of peptide hydrogels in tissue engineering, including soft and hard tissues, will be discussed to analyze the most relevant research trends in this field. |
| first_indexed | 2024-03-11T04:53:08Z |
| format | Article |
| id | doaj.art-9d2ddd1f9a4e48cdb60dc76eedbf99e7 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-03-11T04:53:08Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-9d2ddd1f9a4e48cdb60dc76eedbf99e72023-11-17T19:53:34ZengMDPI AGJournal of Functional Biomaterials2079-49832023-04-0114423310.3390/jfb14040233Peptide-Based Hydrogels: Template Materials for Tissue EngineeringRoya Binaymotlagh0Laura Chronopoulou1Cleofe Palocci2Department of Chemistry, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, ItalyDepartment of Chemistry, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, ItalyDepartment of Chemistry, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, ItalyTissue and organ regeneration are challenging issues, yet they represent the frontier of current research in the biomedical field. Currently, a major problem is the lack of ideal scaffold materials’ definition. As well known, peptide hydrogels have attracted increasing attention in recent years thanks to significant properties such as biocompatibility, biodegradability, good mechanical stability, and tissue-like elasticity. Such properties make them excellent candidates for 3D scaffold materials. In this review, the first aim is to describe the main features of a peptide hydrogel in order to be considered as a 3D scaffold, focusing in particular on mechanical properties, as well as on biodegradability and bioactivity. Then, some recent applications of peptide hydrogels in tissue engineering, including soft and hard tissues, will be discussed to analyze the most relevant research trends in this field.https://www.mdpi.com/2079-4983/14/4/233peptide hydrogelsself-assembly3D scaffoldstissue engineering |
| spellingShingle | Roya Binaymotlagh Laura Chronopoulou Cleofe Palocci Peptide-Based Hydrogels: Template Materials for Tissue Engineering Journal of Functional Biomaterials peptide hydrogels self-assembly 3D scaffolds tissue engineering |
| title | Peptide-Based Hydrogels: Template Materials for Tissue Engineering |
| title_full | Peptide-Based Hydrogels: Template Materials for Tissue Engineering |
| title_fullStr | Peptide-Based Hydrogels: Template Materials for Tissue Engineering |
| title_full_unstemmed | Peptide-Based Hydrogels: Template Materials for Tissue Engineering |
| title_short | Peptide-Based Hydrogels: Template Materials for Tissue Engineering |
| title_sort | peptide based hydrogels template materials for tissue engineering |
| topic | peptide hydrogels self-assembly 3D scaffolds tissue engineering |
| url | https://www.mdpi.com/2079-4983/14/4/233 |
| work_keys_str_mv | AT royabinaymotlagh peptidebasedhydrogelstemplatematerialsfortissueengineering AT laurachronopoulou peptidebasedhydrogelstemplatematerialsfortissueengineering AT cleofepalocci peptidebasedhydrogelstemplatematerialsfortissueengineering |